Cytiva GE Adapter Filter Unit 2 um Polypropylene SS 316L

Cytiva (GE) 18110210 Adapter Filter Unit – 2 µm, Polypropylene

The Cytiva 18110210 (formerly GE Healthcare) is a high-purity adapter filter unit designed for the protection of chromatography columns and sensitive fluidic paths. Featuring a 2 µm porosity polypropylene filter element, this unit effectively captures particulate matter and undissolved solids that could otherwise lead to increased backpressure or column fouling. Specifically engineered for use with ÄKTA chromatography systems and other liquid handling platforms, the 18110210 ensures consistent flow dynamics and extends the operational life of expensive stationary phases. Constructed from premium medical-grade polypropylene, it offers broad chemical resistance and maintains sample integrity by providing a low-extractable, low-protein-binding filtration environment.

Technical Performance and Design

• 2 µm Filtration Efficiency: Provides precise particulate retention, protecting fine-mesh column beds and narrow-bore tubing from blockage while maintaining low resistance to flow.

• High-Purity Polypropylene: The filter and housing are constructed from virgin polypropylene, ensuring compatibility with a wide range of aqueous and organic solvents commonly used in protein purification.

• Integrated Adapter Design: Engineered for seamless installation into standard chromatography fluid paths, allowing for rapid replacement during routine maintenance with minimal system downtime.

• Low Non-Specific Binding: The material properties are optimized to minimize the loss of valuable biological samples, such as proteins, nucleic acids, and monoclonal antibodies, during the filtration process.

Product Specifications

• Catalog Number: 18110210

• Filter Pore Size: 2 µm

• Material: Polypropylene (PP)

• Compatibility: ÄKTA pure, ÄKTA avant, and other high-pressure chromatography systems.

• Chemical Stability: Stable in pH 1–14; resistant to common cleaning-in-place (CIP) reagents.

• Sterility: Non-Sterile (Autoclavable if required by protocol).

Key Benefits & Applications

• Column Protection: Acts as a critical "last line of defense" before the sample or mobile phase enters the chromatography column, preventing irreversible bed damage.

• Protein Purification: Ideal for downstream bioprocessing workflows where maintaining a particulate-free environment is essential for the purity of the final product.

• Robust Industrial Performance: Designed to withstand the pressures and flow rates associated with modern FPLC systems without shedding fibers or compromising seal integrity.

• Cost-Effective Maintenance: Replacing the filter unit is a proactive measure that prevents significantly more expensive repairs to system pumps, valves, and columns.

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