Thermo Scientific Slide-A-Lyzer Buoy Cassette Float 30 Buoys

Thermo Scientific 66430 Slide-A-Lyzer™ Cassette Buoy (White)

The Thermo Scientific 66430 is a specialized flotation accessory designed for use with the original format of Slide-A-Lyzer™ Dialysis Cassettes. Engineered to provide optimal buoyancy, this buoy ensures that the dialysis cassette remains suspended in a vertical orientation within the buffer beaker. This vertical positioning is critical for maximizing the exposed membrane surface area, which facilitates the fastest possible dialysis kinetics. Manufactured from high-density, chemically resistant foam, the 66430 is a reusable lab staple that provides a secure, friction-fit grip on the cassette frame, preventing it from sinking or resting against the container walls where diffusion could be hindered.

Technical Performance and Design

• Optimized Vertical Suspension: Holds the cassette in the ideal orientation to ensure that both sides of the dialysis membrane are fully in contact with the buffer, maintaining a high concentration gradient for efficient salt and contaminant removal.

• Universal Original-Fit: Specifically designed to accommodate the frames of 0.5 ml, 3.0 ml, and 12.0 ml original-style Slide-A-Lyzer™ cassettes.

• High-Density Construction: The closed-cell foam material is non-absorbent and resistant to common laboratory buffers, ensuring long-term durability and consistent buoyancy through repeated use.

• Friction-Fit Security: The precision-cut center slot provides a snug fit that keeps the cassette securely locked in place, even during moderate buffer stirring.

Product Specifications

• Catalog Number: 66430

• Compatible Cassettes: Slide-A-Lyzer™ Original Format (0.5 ml, 3 ml, 12 ml)

• Color: White

• Material: High-Density Synthetic Foam

• Capacity: Holds 1 Cassette per Buoy

• Packaging: Available as individual units or in packs of 10.

Key Benefits & Applications

• Enhanced Dialysis Efficiency: Prevents the cassette from resting at the bottom of the beaker, ensuring that magnetic stir bars can circulate buffer freely around the entire membrane.

• Sample Protection: Keeps the cassette away from the vortex and the stir bar at the bottom of the beaker, reducing the risk of physical damage to the delicate dialysis membrane.

• Benchtop Organization: Allows for easy retrieval of samples from large buffer volumes; the bright white color makes the sample location easy to identify even in large carboys or beakers.

• Reusable Design: Simply rinse with deionized water and air dry between uses, making it a cost-effective solution for routine protein purification and desalting workflows.

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