BIA Separations CIMmultus QA Monolithic Column 1 ml 6 um Pore Size

The BIA Separations 311.5113-6 CIMmultus QA Monolithic Column is a high-performance chromatography column designed for the fast and efficient purification of large biomolecules. The column is equipped with a strong anion exchange (QA) monolithic resin, which is a specialized stationary phase that allows for the separation of biomolecules such as viruses, adeno-associated viruses (AAV), and virus-like particles (VLP) through ionic interactions.

The monolithic design of the column is a key feature, as it provides wide flow-through channels and a rigid, incompressible structure. This allows for convective mass transfer, which is independent of flow rate, enabling high flow rates and rapid purification without sacrificing resolution. This column has a 6 µm pore size and a volume of 1 mL, making it an excellent tool for initial screening, method development, and lab-scale purifications. It is compatible with most liquid chromatography (LC) systems through a standard 10-32 UNF coned port and a 1/16 inch OD tubing connection.

The CIMmultus QA column is a versatile tool that can be used for preparative applications or analytical fingerprinting of process samples. It is sanitizable with 1 M NaOH, and its housing is constructed from reinforced epoxy thermoset materials, providing structural strength comparable to stainless steel. It is suitable for both single-use and multi-use applications, offering flexibility for various bioprocessing needs.