Cytiva GE HiTrap Capto Adhere ImpRes 1 ml Pack of 5 Resin Columns

The Cytiva 17-3715-10 GE HiTrap Capto Adhere ImpRes 1 ml Resin Column is a ready-to-use, pre-packed chromatography column designed for high-resolution protein purifications, particularly for screening and small-scale applications. This column is equipped with BioProcess Capto Adhere ImpRes, a strong anion exchange multimodal resin. Multimodal functionality allows the resin to interact with target molecules through various mechanisms, including ionic and hydrophobic interactions, providing a different selectivity profile compared to traditional ion exchange columns.

This 1 ml resin column is highly effective for removing key impurities such as aggregates, viruses, host cell proteins (HCP), leached protein A, and nucleic acids. It is an excellent choice for the high-resolution polishing of monoclonal antibodies (MAbs) and other recombinant or native proteins, especially as a second or third purification step downstream of a protein A capture step. The high-resolution beads and unique selectivity of the ligand contribute to achieving high yields and purity.

HiTrap Capto Adhere ImpRes columns are often used for screening binding and elution conditions, as well as for small-scale purifications. They offer fast, reproducible, and easy separations in a convenient format, suitable for connection to liquid chromatography systems like ÄKTA systems. This makes the Cytiva 17-3715-10 column a valuable tool for process development and optimization in biopharmaceutical research and manufacturing.