Repligen MidiKros Hollow Fiber Filter mPES 750 kDa

The MidiKros Hollow Fiber Filter Sterile, model D06-E750-05-S, is a filtration device designed for bioprocessing applications requiring sterile and efficient separation of biomolecules. This filter utilizes a modified polyethersulfone (mPES) membrane, a material known for its chemical resistance and low protein binding, which minimizes product loss.

   A key feature of this filter is its 750 kDa (kilodalton) molecular weight cutoff (MWCO). This MWCO defines the size of molecules retained by the filter, making it suitable for separating proteins, antibodies, and other biomolecules from smaller substances. The filter also provides a 370 cm² filtration area, which offers a good balance between processing capacity and manageable size. The filter is provided sterile, a crucial characteristic for maintaining the integrity of biopharmaceutical products and processes.   

MidiKros Hollow Fiber Filters are commonly used in applications such as protein concentration, diafiltration (buffer exchange), and clarification. Their design and membrane properties contribute to efficient and reliable separation of biomolecules in bioprocessing workflows.