Cytiva GE Xampler Ultrafiltration Hollow Fiber Cartridge UFP-300-C-4x2MA

The Cytiva UFP-300-C-4x2MA GE Xampler Ultrafiltration Hollow Fiber Cartridge is a specialized laboratory-scale filtration module designed for the concentration, purification, and diafiltration of biological streams. This cartridge features a 300,000 nominal molecular weight cutoff (300k NMWC). This specific pore size is ideal for retaining very large biomolecules, virus-like particles, and plasmids, or for cell harvesting applications, while allowing smaller proteins and buffer salts to pass through into the permeate.

A key feature of this cartridge is its 1400 cm² effective filtration area, which positions it perfectly for process development, pilot-scale studies, or processing moderate volumes of valuable samples. It utilizes hollow fiber technology operating in a Tangential Flow Filtration (TFF) mode. This design sweeps the surface of the membrane clean during operation, minimizing fouling and gel layer formation. Additionally, the open channel structure of the hollow fibers allows for the gentle processing of shear-sensitive samples, ensuring high product recovery and integrity.

The Cytiva Xampler UFP-300-C-4x2MA is a vital tool in biopharmaceutical research and manufacturing for applications such as viral vector purification, upstream clarification, and the concentration of macromolecular solutions.