Falcon Culture Flask 50 ml with Canted Neck and Vented Cap PS 100 Flasks

Falcon Primaria Cell Culture Flask – 25 cm² Growth Area, 50 mL, Canted Neck, Vented Cap (MPN: 353808)

The Falcon 353808 (now manufactured under the Corning brand) is a high-performance 50 mL rectangular tissue culture flask engineered to enhance the attachment, spreading, and proliferation of fastidious or weakly adherent cell lines. Unlike standard tissue culture surfaces, the Primaria™ growth deck features a unique, permanent nitrogen-containing surface chemistry introduced via a proprietary vacuum gas-plasma treatment process. This modification creates a stable, complex mixture of negatively charged carboxyl groups and positively charged amine groups. Molded from optically clear crystal-grade polystyrene, this 25 cm² flask is designed with an ergonomic canted neck and comes equipped with a blue vented cap featuring an integrated 0.2 µm hydrophobic membrane for safe, continuous gas exchange.

Technical Performance and Design

• Primaria™ Modified Surface Chemistry: The incorporation of nitrogenous functional groups directly into the polystyrene backbone mimics native extracellular matrix attributes, making it the premier option for cell types that attach poorly to traditional, negatively charged TC plastics.

• Integrated 0.2 µm Vented Cap: The screw cap encloses a high-efficiency hydrophobic filter membrane that permits sterile, constant equilibrial gas exchange with incubator atmospheres while serving as an absolute barrier against microbial entries or internal fluid splashes.

• Canted Neck & Splash Barrier: The angled, canted neck configuration provides streamlined pipette and cell scraper access to all internal corners, while an integrated internal splash barrier mitigates the risk of media traveling up into the neck during transport.

• Secure Anti-Tip Stacking: Features a pronounced perimeter rim around the base and top edges, allowing multiple flasks to be locked together securely inside incubators, preventing accidental tipping, structural slippage, or airflow blockages.

Product Specifications

• Catalog Number / MPN: 353808

• Manufacturer / Brand: Corning / Falcon® Primaria™

• Nominal Volume Capacity: 50 mL

• Growth Area: 25 cm² (T25 Equivalent Format)

• Neck Style: Canted Neck (Angled)

• Cap Type / Color: Vented Screw Cap / Light Blue

• Material: Optically Clear Crystal Polystyrene (PS)

• Sterility: Gamma Irradiated Sterile, Certified Non-Pyrogenic (<0.1 EU/mL), and Cytotoxic-Safe

Key Benefits & Applications

• Fastidious Cell & Primary Culture: Heavily utilized for cultivating primary cell cultures, hepatocytes, endothelial cells, neurons, and fastidious tumor lines that fail to achieve stable monolayer formations on standard surfaces.

• No Special Storage Demands: Unlike biological matrix coatings (such as collagen or fibronectin) that carry strict refrigeration rules and brief expiration dates, the Primaria gas-plasma modification is completely stable at room temperature.

• Error-Free Bench Visibility: Shipped in unique, red color-coded medical-style peel pouches that immediately distinguish the premium Primaria flasks from standard tissue-culture vessels on crowded shelving lines.

• Lot-Validated Surface Metrics: Samples from every manufacturing lot undergo strict Electron Scanning for Chemical Analysis (ESCA) testing to verify uniform elemental surface distribution before cleanroom distribution.

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