Novasep Filter Manifold SIUS Low Volume Plate Insert

The Novasep TFPLS-LVFL Filter Manifold is a specialized piece of equipment designed for use in Tangential Flow Filtration (TFF) systems. This manifold is a single-use (SIUS) component, meaning it is intended to be disposed of after one use, which is a key feature for maintaining sterility and eliminating the need for cleaning and validation in biopharmaceutical applications.

A crucial feature of this system is the inclusion of a Low Volume Plate Insert. This insert is designed to minimize the overall fluid hold-up volume within the manifold. In TFF, the hold-up volume is the amount of fluid retained within the system, and reducing it is essential for maximizing product recovery and ensuring that highly concentrated samples can be processed efficiently.

The TFF filter manifold itself is the distribution and collection system for the fluid streams (feed, permeate, and retentate) of the filtration process. This Novasep manifold is a vital tool for lab-scale or process development applications such as protein concentration, diafiltration (buffer exchange), and purification, where minimizing product loss and ensuring aseptic processing are critical.