WaterSep Hollow Fiber Filter Cartridge Researcher12 mPES 1um

WaterSep SU 910 10RES12 SO Researcher12 Green Hollow Fiber Filter – 0.1 µm, 444 cm²

The WaterSep BioSeparations SU 910 10RES12 SO is an advanced hollow fiber filter cartridge engineered for intermediate-scale tangential flow filtration (TFF) and bioprocess scale-up. As a premier component of the single-use "Green Line," this Researcher12 module is gamma-irradiated, glycerin-free, and meticulously designed to eliminate the tedious pre-flushing and cleaning validation required by traditional reusable membranes. Featuring a highly hydrophilic modified Polyethersulfone (m-PES) membrane with a precise 0.1 µm microfiltration pore size and a 1.0 mm fiber inner diameter, it is expertly tailored for cell harvesting, the clarification of high-density culture broths, and viral vector purification. With 444 cm² of effective filtration area and robust sanitary flange connections, the Researcher12 provides highly predictable linear scale-up capabilities for processing batch volumes ranging from 400 mL to 6 Liters.

Technical Performance and Design

• Green Line Ready-to-Use Technology: Manufactured without humectants or storage glycerin, this cartridge generates virtually zero extractables. It can be plumbed directly into the process line and utilized immediately, drastically reducing setup times.

• 0.1 µm m-PES Microfiltration: The 0.1 µm pore rating is the industry standard for retaining whole mammalian cells, bacteria, and large debris while allowing sensitive target proteins and viruses to pass freely into the permeate with minimal non-specific binding.

• Wide 1.0 mm Fiber Lumen: The open-channel, 1.0 mm inner diameter prevents the hollow fibers from clogging when processing highly viscous fluids or streams with high solid content, ensuring a gentle, low-shear fluid path that preserves cell viability.

• Sanitary Flange Connections: The "SO" configuration indicates standard Tri-Clamp/Sanitary connections, providing a secure, leak-proof, and high-pressure interface with pilot-scale bioprocessing skids and stainless steel manifolds.

Product Specifications

• Catalog Number: SU 910 10RES12 SO

• Product Line: Researcher12 (Green Line)

• Pore Size: 0.1 µm

• Membrane Material: Modified Polyethersulfone (m-PES)

• Fiber Inner Diameter (ID): 1.0 mm

• Effective Filtration Area: 444 cm²

• Connections: Sanitary Flange / Tri-Clamp (SO)

• Sterility: Single-Use, Pre-sterilized (Gamma Irradiated)

Key Benefits & Applications

• Bridging R&D and Production: The 444 cm² surface area is perfectly scaled for process optimization, pilot studies, and the production of early-phase clinical materials before transitioning to massive multi-square-meter modules.

• High-Density Cell Harvest: The ideal single-use solution for clarifying dense mammalian (CHO), bacterial, and yeast cultures, replacing the need for messy, high-maintenance centrifugation steps.

• Secure Fluid Dynamics: Upgrading to sanitary flanges ensures that the filtration loop can safely handle the elevated backpressures required for prolonged perfusion and continuous diafiltration without the risk of tubing blowouts.

• Maximized Operational Efficiency: Completely bypasses the hours of labor and massive volumes of high-purity water usually required for Clean-in-Place (CIP) and Sterilize-in-Place (SIP) validation.

All product names, logos, and brands are property of their respective owners.