Millipore Pellicon 2 Mini Cassette with Biomax Membrane 300 kDa
The Millipore P2B300C01 Pellicon 2 Mini Cassette is a tangential flow filtration (TFF) device used for concentrating, purifying, and diafiltering biomolecules in laboratory and pilot-scale applications. This specific mini cassette utilizes a Biomax membrane with a 300 kDa (kilodalton) molecular weight cut-off (MWCO). Mini cassettes, as the name suggests, are designed for smaller-scale processing, making them suitable for research and process development.
The Biomax membrane, a key component of this cassette, is a regenerated cellulose membrane. This type of membrane is valued for its low protein binding characteristics, which minimizes sample loss due to adsorption to the membrane surface. Additionally, Biomax membranes offer broad chemical compatibility, allowing them to be used with a wide range of buffers, salts, and other reagents commonly used in bioprocessing.
The 300 kDa MWCO signifies the membrane's ability to selectively retain molecules based on their size. Molecules larger than 300 kDa are retained by the membrane, while smaller molecules, such as salts, buffers, and smaller proteins, pass through. This makes the cassette suitable for concentrating or purifying target molecules larger than this size. Tangential flow filtration (TFF), also known as crossflow filtration, is the operating principle behind this device. In TFF, the feed stream flows tangentially across the membrane surface, which minimizes membrane fouling and allows for efficient processing of larger volumes compared to traditional dead-end filtration.
The Millipore P2B300C01 Pellicon 2 Mini Cassette is therefore a valuable tool for various bioprocessing applications, including protein purification, antibody concentration, and virus concentration or diafiltration.
Please note that Life Sciences Trading is not a factory-authorized distributor of the products listed in this store. The items have been acquired as surplus from leading life sciences companies.