Thermo Scientific 88528 Protein Concentrator 10K MWCO 20 ml Case of 25

The Thermo Scientific 88528 Protein Concentrator is a disposable ultrafiltration device designed to simplify the process of concentrating, desalting, and buffer exchanging biological samples. This particular concentrator has a 10K MWCO (molecular weight cut-off) and can hold up to 20 ml of sample, making it suitable for concentrating proteins and other macromolecules larger than 10 kDa.

The concentrator uses a vertical polyethersulfone (PES) membrane, which is known for its low protein binding characteristics. This helps to ensure high recovery of your target protein, minimizing losses due to non-specific binding to the membrane.  It is designed for use with standard centrifuges, allowing for quick and efficient concentration.  To further prevent sample loss, the device has a dead-stop volume, which means you can spin the sample without worrying about spinning it to complete dryness.

This type of concentrator is widely used in various research and laboratory settings for applications such as concentrating protein solutions prior to techniques like SDS-PAGE or protein crystallization, removing salts and other small molecules from protein samples, and transferring proteins into a different buffer system. The Thermo Scientific 88528 Protein Concentrator provides a convenient and reliable way to process biological samples, ultimately helping researchers prepare their samples for downstream applications.