Corning Erlenmeyer Flask 125 ml Vent Cap Baffled Polycarbonate Case of 50 Flasks

Corning 431405 Erlenmeyer Culture Flask – 125 mL, Baffled Bottom, Vent Cap, Sterile

The Corning 431405 is a high-performance 125 mL Erlenmeyer flask designed for the cultivation of suspension cell lines, bacteria, and yeast. Manufactured from medical-grade, high-clarity polycarbonate, this flask provides the transparency of glass with the safety and durability of shatterproof plastic. The flask features a molded-in baffled bottom, which promotes vigorous agitation and increases the surface-to-volume ratio to optimize gas exchange. Each flask is supplied individually wrapped and gamma-irradiated to ensure maximum sterility (SAL 10⁻⁶). Equipped with a 38 mm vented screw cap featuring a 0.2 µm hydrophobic membrane, the 431405 allows for continuous, sterile gas exchange while maintaining a secure barrier against contamination.

Technical Performance and Design

• Molded-in Baffled Bottom: The triple-baffle design creates a turbulent flow in the media during orbital shaking, significantly enhancing oxygenation for high-demand aerobic cultures.

• 0.2 µm Vented Cap: The breathable cap ensures consistent gas exchange while preventing the entry of microorganisms, making it ideal for CO2 incubators.

• Individually Wrapped: Each flask is hermetically sealed in its own medical-grade packaging, preventing "cross-contamination" of unused stock and ensuring aseptic integrity until the moment of use.

• High-Clarity Polycarbonate: Constructed from USP Class VI resin, offering excellent visibility for monitoring cell density and media color while providing the impact resistance needed for high-speed shaking.

Product Specifications

• Catalog Number: 431405

• Capacity: 125 mL

• Material: Polycarbonate (PC)

• Bottom Style: Baffled

• Cap Size/Style: 38 mm Vented Cap

• Sterility: Sterile (Gamma Irradiated, SAL 10⁻⁶)

• Certifications: Non-pyrogenic, Non-cytotoxic, and RNase/DNase-free.

Key Benefits & Applications

• Aerobic Fermentation: The baffled geometry is the gold standard for E. coli and yeast cultures that require high oxygen levels to achieve maximum biomass.

• Mammalian Cell Culture: Frequently used for the expansion of CHO, HEK293, and other suspension lines where sterile gas exchange is critical.

• Disposable Efficiency: The single-use format eliminates the risks and costs associated with cleaning, autoclaving, and validation of glass flasks.

• Secure Tracking: Features molded-in graduations for accurate volume measurement and a large writing area for secure sample identification.

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