Corning Erlenmeyer Flask 250 ml with Vent Cap PC Total of 50 Flasks

Corning 431144 Erlenmeyer Flask – 250 mL, Polycarbonate, Vent Cap

The Corning 431144 is a high-quality, single-use Erlenmeyer flask designed for the cultivation of mammalian cells, bacteria, and fungi in shaker-incubator applications. Manufactured from optically clear, medical-grade polycarbonate, this 250 mL flask provides a robust and shatterproof alternative to traditional glass. The flask is equipped with a blue polypropylene (PP) vent cap, which features an integrated 0.2 micron hydrophobic membrane. This allows for consistent and sterile gas exchange while protecting the culture from external contaminants and preventing leakage during vigorous agitation. Sterilized via gamma irradiation, the 431144 is a "ready-to-use" solution for critical bioprocessing and R&D laboratory workflows.

Technical Performance and Design

• 0.2 µm Hydrophobic Vent Cap: The integrated membrane ensures a sterile environment for continuous oxygenation and carbon dioxide exchange, making it ideal for aerobic cultures and CO2 incubators.

• Shatterproof Polycarbonate Construction: Offers the clarity of glass with the safety and durability of high-impact plastic, reducing the risk of sample loss due to breakage during high-speed shaking.

• Molded-in Graduations: Features clear, easy-to-read volume markings (accurate to ±5%) for quick measurement and media preparation.

• Gamma Sterile Packaging: Certified non-pyrogenic and sterile (SAL 10⁻⁶), eliminating the need for autoclaving and reducing the turnaround time between experiments.

Product Specifications

• Catalog Number: 431144

• Capacity: 250 mL

• Flask Material: Polycarbonate (USP Class VI)

• Cap Material: Polypropylene (PP)

• Cap Type: Vent Cap (0.2 µm Membrane)

• Base Style: Plain Bottom (Flat)

• Sterility: Sterile (Gamma Irradiated)

Key Benefits & Applications

• Cell Culture Scale-up: The industry-standard choice for pilot-scale expansion of CHO cells, HEK293 cells, and other mammalian suspension cultures.

• Suspension Culture: Optimized for use on orbital shakers, ensuring excellent fluid dynamics and oxygen transfer rates without sacrificing sterility.

• Media Storage & Prep: The secure vent cap allows for the storage of sensitive reagents that require pressure equalization without exposing the contents to the lab environment.

• Closed-System Design: Minimizes the risk of cross-contamination compared to traditional "loosened cap" techniques, providing more reliable and reproducible results.

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