Corning Microplate with Lid 384 Well 90 ul PS Round Bottom 5 Plates

The Corning 4516 Microplate is a specialized 96-well plate designed for advanced cell culture applications, particularly those involving three-dimensional (3D) cell cultures or assays where cell attachment is undesirable. This microplate features a black polystyrene construction, which is crucial for minimizing background fluorescence and light scatter, thus enhancing the signal-to-noise ratio in sensitive assays. It comes with a lid to maintain a controlled environment within the wells.

A key characteristic of this plate is its ultra-low attachment surface, which is specifically treated to prevent cell adhesion. This is essential for promoting the formation of spheroids, organoids, or other 3D cell aggregates, which are increasingly important models for studying cell behavior and drug responses. The plate also has a clear round bottom, which allows for microscopic imaging and observation of cells or spheroids within the wells. The round bottom shape is beneficial for cell aggregation, as it guides cells to the center of the well. The Corning 4516 Microplate is a valuable tool in fields such as cancer research, stem cell biology, and drug discovery, where controlling cell attachment and studying 3D cell structures are critical.