Cytiva CellBag Disposable Bioreactor 0.5 to 5 L

Cytiva CB0010L10-34 CellBag Disposable Bioreactor (10L)

The Cytiva CB0010L10-34 is a premium 10-liter single-use bioreactor chamber designed for use with WAVE Bioreactor rocking platforms. Manufactured from high-integrity, multi-layer biocompatible polymer film, this CellBag provides a sterile, closed environment for the cultivation of sensitive mammalian, insect, and plant cell lines. The system utilizes a unique rocking motion to induce waves in the culture media, providing excellent oxygen transfer and nutrient distribution with extremely low shear stress. Each bag is delivered pre-sterilized and fully integrated with inlet/outlet filters, sampling ports, and fluid transfer lines, effectively eliminating the need for cleaning and sterilization validation while minimizing the risk of cross-contamination in GMP-regulated environments.

Technical Performance and Design

• Low-Shear Wave Aeration: The rocking motion provides efficient gas-liquid mass transfer without the need for an internal impeller, making it ideal for fragile cell types and high-density suspension cultures.

• Advanced Film Technology: Constructed from medical-grade, USP Class VI polymer film with an exceptionally low extractables and leachables profile to ensure maximum cell viability and product purity.

• Fully Integrated Closed System: Features pre-installed 0.2 µm hydrophobic air filters for sterile gas exchange, as well as specialized ports for aseptic sampling and reagent addition.

• Plug-and-Play Compatibility: Specifically optimized for use with Cytiva WAVE Bioreactor 25 and older 2/10 systems, ensuring reliable sensor integration and temperature control.

Product Specifications

• Catalog Number: CB0010L10-34

• Total Volume: 10 Liters

• Working Volume Range: Typically 0.5 L to 5.0 L (depending on application).

• Material: Multi-layer USP Class VI Polyethylene-based film.

• Sterility: Sterile (Gamma Irradiated).

• Ports: Includes gas inlet/outlet filters, clear C-Flex tubing, and needleless sampling ports.

• Purity: Certified Non-Pyrogenic and Non-Cytotoxic.

Key Benefits & Applications

• Inoculum Scale-Up: The preferred vessel for seed train expansion, providing a reliable bridge between small-scale flasks and large-production bioreactors.

• Cell & Gene Therapy: Ideal for the production of viral vectors and autologous cell therapies in a highly controlled, closed-system environment.

• Biopharmaceutical Production: Extensively used for the transient expression of monoclonal antibodies and recombinant proteins.

• Rapid Deployment: Single-use design enables immediate batch turnover, reducing facility downtime and capital expenditure on cleaning-in-place (CIP) infrastructure.

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