Cytiva Hydraulic Inlet Ball Valve for FineLINE Columns

Cytiva (GE) 18110210 Adapter Filter Unit – 2 µm, Polypropylene

The Cytiva 18110537 is a high-precision hydraulic inlet ball valve specifically engineered for use with FineLINE™ 70, 100, 200, and 350 chromatography columns. This genuine OEM component is a critical part of the column’s hydraulic actuation system, responsible for controlling the inlet flow that drives the internal piston. Designed to withstand the high pressures required for efficient resin bed compression, the 18110537 ensures a secure, leak-proof seal and smooth manual operation. Manufactured from corrosion-resistant materials, this valve is built to maintain the mechanical integrity of the FineLINE hydraulic station, facilitating the precise piston positioning necessary for optimal column packing, unpacking, and cleaning-in-place (CIP) workflows.

Technical Performance and Design

• Precision Pressure Control: Engineered to manage the hydraulic force required to actuate the FineLINE piston, allowing for the exacting compression of the stationary phase to reach targeted bed heights.

• Durable Ball Valve Architecture: Features a robust internal ball mechanism that provides a superior "bubble-tight" shut-off, preventing hydraulic fluid bypass and unintended piston movement during operation.

• Corrosion-Resistant Construction: Built with high-grade industrial materials capable of withstanding the humid and chemically diverse environments found in biopharmaceutical pilot and production plants.

• Seamless System Integration: As a genuine Watson-Marlow/Cytiva replacement part, it features the exact threading and port dimensions required for a direct-fit replacement on FineLINE 70–350 hydraulic manifolds.

Product Specifications

• Catalog Number: 18110537

• Component Type: Hydraulic Inlet Valve (Ball Valve)

• Compatibility: FineLINE™ 70, FineLINE™ 100, FineLINE™ 200, and FineLINE™ 350 Columns.

• Application: Piston Actuation and Hydraulic Flow Control.

• Material: High-grade Stainless Steel / Industrial Polymers.

• Function: Manual Inlet Control for Hydraulic Station.

Key Benefits & Applications

• Ensures Column Bed Integrity: By providing reliable hydraulic shut-off, the valve prevents pressure loss that could lead to bed expansion or cracking during high-resolution purification.

• Facilitates Scale-Up: Supports the robust operation of FineLINE columns in pilot-scale and large-scale manufacturing of vaccines, monoclonal antibodies, and recombinant proteins.

• Minimized Maintenance Downtime: The "drop-in" design allows facility engineers to quickly replace worn valves without extensive system recalibration.

• Validated Performance: Using genuine Cytiva parts ensures that the column remains within its original manufacturer-validated specifications for safety and performance.

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