Medicons Disposable Disaggregator 50 um Separator Screen 28 Filters

Medicons 79500S Disposable Disaggregator (Max) – 50 µm, 16 mL, Sterile

The Medicons 79500S is an advanced, single-use mechanical disaggregator engineered to rapidly reduce solid tissue into a uniform cell suspension. Unlike traditional manual mincing or harsh enzymatic digestions, this closed system utilizes an internal stainless steel screen featuring approximately 250 hexagonal bore-holes, each surrounded by six precision microblades. As the machine rotates the tissue against the blades, cells are gently separated and forced through the 50 µm mesh, strictly limiting the size of the passing cell clusters and preventing destructive acoustic or thermal trauma. Designed as the "Max" high-volume variant, the 79500S can accommodate up to 1.5 grams of tissue and 16 mL of buffer, making it highly efficient for bulk sample processing. Arriving certified sterile, it entirely eliminates the need for between-sample cleaning and validation, completely preventing cross-contamination in critical clinical and research workflows.

Technical Performance and Design

• Mechanical Microblades: The sophisticated stainless steel cutting matrix actively shears tissue into a fine suspension without inducing the shear stress or heat damage commonly associated with standard laboratory homogenizers.

• 50 µm Separator Screen: The absolute 50-micron mesh effectively traps larger debris, stroma, and connective tissue, yielding a highly uniform single-cell or small-cluster suspension that is immediately ready for downstream filtration and analysis.

• High-Volume Capacity (Max 16 mL): While standard Medicons hold only 1 mL, the 79500S model safely processes significantly larger tissue masses (up to 1.5 g) and up to 16 mL of suspension buffer, drastically improving high-throughput preparation.

• Closed, Disposable System: The self-contained HDPE casing securely encapsulates the sample during disaggregation, protecting the operator from infectious aerosols while ensuring the tissue remains sterile.

Product Specifications

• Catalog Number: 79500S

• Pore Size / Mesh: 50 µm

• Maximum Volume: 16 mL Buffer / up to 1.5 g Tissue

• Housing Material: High-Density Polyethylene (HDPE)

• Screen Material: Stainless Steel

• Sterility: Sterile ("S" designation)

Key Benefits & Applications

• Flow Cytometry Prep: The industry gold standard for rapidly processing solid tumors, lymph nodes, and organ tissues into highly viable, single-cell suspensions for FACS (Fluorescence-Activated Cell Sorting) analysis.

• Enzyme-Free Isolation: Highly effective at mechanical disaggregation, allowing researchers to isolate functional cells without using aggressive proteolytic enzymes (like trypsin) that can strip sensitive cell-surface markers.

• Standardized Reproducibility: Completely eliminates operator-to-operator variability caused by manual scalpel mincing, ensuring that cell yields and tissue dissociation times are perfectly consistent across laboratory batches.

• Primary Cell Culture: The sterile format guarantees that isolated cells can be safely seeded directly into culture flasks for expansion without the risk of bacterial or fungal contamination.

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Expiration: 09/2014.