Applikon Condenser for 1-5 L Bioreactors

Applikon CLS-1380-27 Stainless Steel Exhaust Condenser (165mm, M18 x 1.5 Thread)

The Applikon CLS-1380-27 is a precision-engineered exhaust gas condenser designed for 1-liter to 7-liter bioreactor systems. This stainless steel unit serves as a high-efficiency heat exchanger, cooling the exhaust gas stream to liquefy water vapor and return it to the culture vessel. This is a critical process for maintaining constant osmolarity and preventing media loss during long-term fermentation. Featuring a standard M18 x 1.5 threaded connection, this condenser is designed for direct headplate mounting, providing a secure, leak-proof seal that protects downstream exhaust filters from moisture-induced clogging.

Technical Performance and Design

• Standard M18 x 1.5 Interface: Featuring a 17.7mm - 18mm outer thread diameter, this condenser fits the standard medium-sized ports found on Applikon, Broadley-James, and Chemglass headplates.

• Efficient Moisture Removal: The internal cooling jacket strips water vapor from the exit gas, preventing the "wetting out" of hydrophobic 0.22 µm exhaust filters which can lead to vessel over-pressurization.

• 316L Stainless Steel Construction: Manufactured from electropolished, pharmaceutical-grade 316L stainless steel for maximum corrosion resistance and longevity in demanding bioprocessing environments.

• Compact 165mm Footprint: Specifically sized for benchtop bioreactors (1-7L), providing optimal cooling surface area without creating excessive headspace height requirements.

Product Specifications

• Catalog Number: CLS-1380-27

• Thread Size: M18 x 1.5 (Metric)

• Thread Outer Diameter: ~17.7mm - 18mm

• Overall Length: 165 mm

• Material: 316L Stainless Steel

• Coolant Connections: 1/4-inch (6.4mm) Serrated Hose Barbs

• Compatibility: Fits standard M18 ports on Applikon® and Broadley-James® style headplates.

Key Benefits & Applications

• Evaporation Control: Essential for maintaining precise media concentrations in batch, fed-batch, and perfusion cultures where aeration rates are high.

• Filter Longevity: By condensing vapor before it reaches the exhaust filter, this unit significantly reduces the frequency of filter changes and prevents process interruptions.

• Fully Autoclavable: The robust all-metal design allows the condenser to be sterilized in-place on the headplate, ensuring a closed, sterile system from the start of the run.

• Easy Integration: Standardized threads and hose barb connections allow for rapid setup with recirculating chillers or laboratory cold water lines.

Used; in great condition!

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