Azlet Micro-Osmotic Pump and Flow Moderator Kit 0.11 ul/hr Total of 10 Pumps

ALZET Model 1004 Micro-Osmotic Pump and Flow Moderator Kit, 0.11 µL/hr (Model 1004) – Pack of 10 Pumps

The ALZET Model 1004 Micro-Osmotic Pump is a miniature, implantable infusion system engineered for continuous, controlled delivery of research agents in mice, young rats, and other small laboratory animals. Utilizing osmotic displacement, this micro-pump delivers test agents—including peptides, proteins, oligonucleotides, gene therapy vectors, and small molecules—at a constant rate of 0.11 µL/hr for up to 28 days without external batteries, sensors, or software. Operating on the principle of osmotic pressure differential, the pump draws body fluids into its outer osmotic sleeve, compressing an internal flexible reservoir to displace the compound through a central flow moderator. Supplied as a complete kit containing 10 micro-osmotic pumps and 10 stainless steel flow moderators, this system ensures highly reproducible, target-specific systemic or targeted dosing in preclinical research.

Technical Performance & Structural Attributes

• Continuous & Unattended Agent Delivery: Eliminates the need for repetitive daily injections or restraint stress, ensuring stable, steady-state plasma concentration levels.
• Self-Powered Osmotic Engine: High-density salt osmotic sleeve continuously absorbs ambient tissue fluid across a semi-permeable outer membrane to drive delivery.
• Inert Biocompatible Construction: Constructed from medical-grade synthetic polymers and titanium flow components to preserve compound stability and minimize tissue reaction.
• Targeted Micro-Cannulated Delivery: Easily connects to specialized ALZET brain infusion kits or vascular catheters for targeted organ, central nervous system, or intra-arterial administration.

Product Specifications

• Catalog / Model Number: Model 1004
• Primary Manufacturer: DURECT Corporation / ALZET Osmotic Pumps
• Nominal Delivery Rate: 0.11 µL/hr (± 0.02 µL/hr)
• Nominal Reservoir Volume: 100 µL
• Pumping Duration: 28 Days (4 Weeks)
• Dimensions: 1.5 cm Length x 0.6 cm Diameter
• Pump Weight (Empty): 0.4 g
• Minimum Animal Size: Mice (Body Weight ≥ 10 g), Young Rats
• Sterility Status: Pre-Sterilized (Ethylene Oxide)
• Packaging Configuration: Kit of 10 Micro-Osmotic Pumps with 10 Flow Moderators & Filling Tube Accessories

Key Benefits & Applications

• Preclinical Pharmacokinetics & Toxicology: Provides long-term, zero-order drug kinetics for chronic dosing studies in oncology, immunology, and metabolic research.
• Central Nervous System (CNS) Research: Connects with brain cannula systems for direct, targeted intracerebroventricular (i.c.v.) or intrathecal infusion.
• Animal Welfare & Stress Reduction: Eliminates handling stress and needle trauma associated with chronic daily dosing regimens in small animal models.

All product names, logos, and brands are property of their respective owners. ALZET is a registered trademark of DURECT Corporation.