Corning Costar TC-Treated 24 Well Microplate Flat Bottom Sterile Case of 100 Plates

Corning® Costar® 24-Well Clear Flat-Bottom Tissue Culture-Treated Microplate (3524) – Case of 100

The Corning® Costar® 3524 is a standard laboratory multi-well plate engineered for scaling up cell cultures, processing functional cell-based assays, and executing low-volume sample preparations. Featuring Corning's validated Tissue Culture (TC) surface treatment, the virgin polystyrene matrix undergoes an advanced atmospheric modification that permanently embeds hydrophilic oxygen groups into the plastic layer, maximizing the attachment and spreading of anchorage-dependent cell lines. Supplied pre-sterilized with non-reversible condensation-ring lids in a case of 100 plates, this clear flat-bottom microplate guarantees cross-contamination control and uniform downstream microscopic analysis.

Technical Performance & Design

• Hydrophilic Tissue Culture Treatment: Subjected to an industrial vacuum-gas plasma discharge that turns the naturally hydrophobic polystyrene surface into a highly uniform, hydrophilic cell attachment boundary layer.
• Optically Clear Flat-Bottom Wells: Molded from high-purity, optical-grade virgin polystyrene to ensure premium side-wall and bottom thickness consistencies, delivering exceptional planar clarity for inverted phase-contrast microscopy and automated plate readers.
• Asymmetric Non-Reversible Lid: Accompanied by a custom-molded polystyrene lid featuring a unique orientation design to eliminate manual capping placement errors and prevent accidental cross-well contamination.
• Molded Evaporation Control Rings: The interior ceiling of the lid incorporates individual condensation rings that align precisely above each well, limiting evaporation rates, maintaining uniform osmotic pressures, and restricting cross-well aerosol migration.

Product Specifications

• Model Number / Part No: 3524 (Cross-referenced under factory SKU CLS3524)
• Manufacturer Line: Corning® Costar® Multiple Well Plates
• Plate Array Format: 24-Well Grid Matrix (4 Rows x 6 Columns Layout)
• Well Shape & Bottom: Cylindrical Wells with an Ultra-Flat (F) Bottom
• Color Morphology: 100% Optically Translucent Clear
• Volumetric Dimensions: Total Well Volume: 3.4 mL; Recommended Working Volume: 0.38 mL to 0.57 mL; Total Growth Surface Area: 1.9 cm² per well
• Sterility Specification: Sterile (Pre-sterilized via validated gamma irradiation protocols)
• Purity Verification: Certified non-pyrogenic and endotoxin-free (less than 0.1 EU/mL)
• Packaging Configuration: Case of 100 Plates (Individually wrapped packages with lids included)

Key Benefits & Applications

• Adherent Cell Maintenance & Scaling: Highly recommended for standard line expansions, downstream cell harvesting, and seeding target transfection hosts like HeLa, CHO-K1, and primary fibroblast lines.
• Multi-Point Assay Transfection: The 24-well grid footprint serves as the perfect dimensional compromise between low-throughput culture dishes and high-density 96-well configurations, allowing ample surface area for cell protein expressions or multi-variable drug exposure runs.
• Automated Deck Standardization: Built with a uniform raised bead perimeter to aid structural stacking stability while satisfying global ANSI/SLAS 1-2004 multi-well plate dimensions for seamless integration with robotic pickers, automated liquid handlers, and multi-mode plate readers.
• Alphanumeric Spatial Identification: Molded with crisp, high-contrast alphanumeric row and column grid coordinate lines to simplify manual pipetting sequences and tracking profiles.

Corning® and Costar® are registered trademarks of Corning, Inc. Catalog reference 3524 specifies the standard tissue culture-treated, clear flat-bottom 24-well array. For suspension-based or non-adherent lines (such as hybridomas or primary lymphocytes), alternative ultra-low attachment or non-treated plates must be sourced independently.