{"product_id":"corning-culture-flasks-3l-vented-cap-erlenmeyer-fernbach-sterile","title":"Corning Culture Flask 3L Vented Cap Erlenmeyer Fernbach Sterile Case of 4","description":"\u003ch3\u003eCorning 3L Polycarbonate Erlenmeyer Cell Culture Flask – Fernbach Design, Plain Flat Bottom, 0.2 µm Vented Cap, Optically Clear, Gamma Sterile (MPN: 431252)\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eExpiration: 2025-04-01.\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eThe Corning Life Sciences 431252 (also cataloged as CLS431252 or 431252-CL) is a high-performance, single-use 3-liter bioprocess shaker flask engineered for high-yield cell culture expansion, media preparation, and recombinant protein expression. Manufactured from high-clarity, break-resistant virgin polycarbonate (USP Class VI), this flask features a classic wide-base Fernbach geometry designed to significantly increase liquid surface area and optimize gas exchange dynamics during orbital shaking. Outfitted with an orange polypropylene wide-mouth screw cap containing an integrated 0.2 µm hydrophobic membrane filter, the 431252 permits continuous, sterile gas exchange while providing an unyielding barrier against airborne micro-contaminants and fluid leakage. Supplied gamma-irradiated sterile and certified non-pyrogenic as well as RNase- and DNase-free, this 3000 mL vessel serves as an industry-standard scale-up link across biopharmaceutical development, cell therapy manufacturing, and fermentation cores.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance and Structural Design\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSurface-Maximizing Fernbach Design:\u003c\/b\u003e Engineered with a wide, squat Fernbach base footprint that dramatically increases the liquid-to-gas surface interface. This profile maximizes passive oxygenation rates and carbon dioxide stripping without requiring forced sparging systems.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eUSP Class VI Polycarbonate Matrix:\u003c\/b\u003e Injection-molded from medical-grade, shatterproof polycarbonate. This material provides crystal-clear optical transparency for rapid visual turbidity checks while withstanding structural stress during high-RPM orbital shaking routines.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e0.2 µm Hydrophobic Membrane Vent Cap:\u003c\/b\u003e Outfitted with a polypropylene threaded cap featuring an integrated 0.2 µm hydrophobic PTFE membrane. The microporous filter ensures continuous, sterile aeration during incubation loops without risking aerosolized media blowouts or environmental contamination.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePlain Flat-Bottom Hydrodynamics:\u003c\/b\u003e Features a smooth, non-baffled plain flat bottom. This non-baffled interior surface reduces fluid shear stress, making it the preferred choice for shear-sensitive mammalian cells, insect cell lines, and delicate suspension cultures.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number \/ MPN:\u003c\/b\u003e 431252 (Cross-listed as CLS431252 \/ 431252-CL)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eManufacturer \/ Brand:\u003c\/b\u003e Corning Life Sciences\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eNominal Working Volumetric Capacity:\u003c\/b\u003e 3000 mL (3 Liters)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFlask Geometry \u0026amp; Bottom Style:\u003c\/b\u003e Conical Fernbach Design with a Plain Flat Bottom (Non-baffled format)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaterial Composition:\u003c\/b\u003e Optical-Grade Polycarbonate (PC) Flask Body with Polypropylene (PP) Closure\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCap Type \u0026amp; Color:\u003c\/b\u003e Wide-Mouth Threaded Vent Cap with 0.2 µm Membrane (Orange)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eOverall Physical Exterior Dimensions:\u003c\/b\u003e Approximately 9.06 inches Base Diameter x 9.92 inches Overall Height (230 mm Diameter x 252 mm Height)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBiological Purity Status:\u003c\/b\u003e Gamma Irradiated Sterile, Non-Pyrogenic, RNase-free, and DNase-free\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits and Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSuspension Mammalian \u0026amp; Insect Cell Scale-Up:\u003c\/b\u003e The standard baseline choice for scaling up CHO, HEK293, and Sf9\/Sf21 suspension cell lines before inoculation into large seed-train bioreactors.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eShear-Sensitive Cell Line Protection:\u003c\/b\u003e The plain (non-baffled) bottom profile minimizes turbulent shear forces, protecting delicate cell membranes from mechanical lysis during continuous orbital shaking.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eUniversal Orbital Shaker Compatibility:\u003c\/b\u003e Drops smoothly into standard high-capacity 3L shaker clamps and sticky-mat platforms across major benchtop and incubator shakers.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eAseptic Reagent \u0026amp; Buffer Holding:\u003c\/b\u003e Excellent single-use sterile vessel choice for preparing, storing, and transferring sterile culture media, feed solutions, or intermediate process buffers.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Corning","offers":[{"title":"Default Title","offer_id":47225136021756,"sku":"1260","price":213.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/corning-culture-flasks-3l-vented-cap-erlenmeyer-fernbach-sterile-case-of-4-lab-culture-flask-corning-245708.jpg?v=1749778824","url":"https:\/\/lifesciencestrading.com\/es\/products\/corning-culture-flasks-3l-vented-cap-erlenmeyer-fernbach-sterile","provider":"Life Sciences Trading","version":"1.0","type":"link"}