Corning Storage Bottle 250 ml Easy Grip Sterile Case of 24 Bottles

Corning 250 mL Easy-Grip Polystyrene Storage Bottles – 45 mm High-Density Polyethylene Plug Seal Cap, Low-Profile Indented Sidewalls, Vacuum Filter Receiver Compatible, Gamma Sterile, Non-Pyrogenic (MPN: 430281)

The Corning Life Sciences 430281 (also cataloged as CLS430281 or 430281-EA) is a research-grade, single-use laboratory storage bottle designed for the safe collection, preparation, and sterile holding of tissue culture media, sera, biological buffers, and aqueous reagents. Molded from crystal-clear virgin polystyrene (PS), this 250 mL vessel features Corning's low-profile "Easy-Grip" side indentations, providing technicians with a secure, slip-free handhold during wet-bench procedures and hood manipulations. The bottle is fitted with an orange, heavy-duty 45 mm high-density polyethylene (HDPE) plug seal screw cap that establishes a leak-proof hermetic barrier against environmental contaminants and ambient evaporation. Engineered with high-contrast, molded-in volumetric graduations and a standard 45 mm wide-mouth neck thread, this sterile container serves as both a standalone media storage bottle and a direct receiver flask for 45 mm bottle-top vacuum filtration units.

Technical Performance and Structural Design

• Ergonomic Easy-Grip Sidewall Indentations: Designed with contoured, recessed side channels that fit comfortably in hand. This physical grip profile prevents slipping when handling bottles wearing wet nitrile gloves inside laminar flow hoods.

• 45 mm HDPE Plug Seal Closure: Features an orange high-density polyethylene threaded cap with an internal plug seal ring. The plug compresses against the inner neck wall to create an airtight, liquid-tight seal that prevents leakage and guards against airborne microbial contamination.

• Vacuum Filtration System Receiver Interoperability: Built with a standardized 45 mm wide-mouth neck thread. This geometry allows the bottle to screw directly onto Corning bottle-top vacuum filter units (such as PES, CA, or Nylon membrane systems), serving as a clean receiver vessel for sterile filtration routines.

• Certified Biological Purity: Gamma-irradiated to guarantee sterility and certified non-pyrogenic (endotoxin levels less than 0.1 EU/mL), safeguarding sensitive primary cell cultures and molecular reagents from biological degradation.

Product Specifications

• Catalog Number / MPN: 430281 (Cross-listed as CLS430281 / 430281-CS / Fisher 09-761-4)

• Manufacturer / Brand: Corning Life Sciences

• Volumetric Capacity Parameters: 250 mL nominal working volume

• Material Composition: Optical-Grade Virgin Polystyrene (Bottle Body) / High-Density Polyethylene (Cap)

• Neck Thread & Closure Size: 45 mm Wide-Mouth Threaded Neck

• Cap Design & Color: Orange HDPE Plug Seal Screw Closure

• Graduation Scale Range: Molded-in metric volumetric graduations (25 mL to 250 mL scale)

• Sterility & Thermal Limitations: Gamma-Sterile, Single-Use Disposable (Do not autoclave; maximum thermal durability 80 C)

Key Benefits and Applications

• Sterile Media & Serum Storage: The standard workhorse container for storing sterile cell culture media, fetal bovine serum (FBS), trypsin solutions, and specialized growth factors.

• Bottle-Top Filtration Receiver: Connects directly beneath 45 mm vacuum filter funnels, allowing researchers to filter and store sterile reagents in a single continuous step without transferring liquids between containers.

• Aqueous Buffer Aliquoting: Ideal for preparing and organizing sterile salt solutions, molecular biology buffers, and chromatography eluates at the bench.

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