{"product_id":"milenyi-biotec-automacs-column-sterile","title":"Milenyi Biotec AutoMACS Column Sterile Pack of 8 Columns","description":"\u003ch3\u003eMiltenyi Biotec® autoMACS® Columns, Sterile (130-021-101) – Pack of 8\u003c\/h3\u003e\n\u003cp\u003eThe Miltenyi Biotec® 130-021-101 is a specialized, high-performance automated magnetic cell separation consumable engineered exclusively for use with the autoMACS® and autoMACS® Pro Automated Cell Separator instruments. Utilizing an innovative hydrophilic matrix of ferromagnetic spheres, these columns generate an ultra-intense, localized magnetic gradient when positioned within the instrument's magnetic field block. This design enables the high-purity isolation of magnetically labeled target cell populations. Supplied pre-sterilized as a factory pack of 8 columns, this single-use consumable guarantees exceptional viability and high recovery rates across automated sorting runs.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance \u0026amp; Design\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHigh-Gradient Ferromagnetic Matrix: Packed with precision-engineered, biocompatible steel spheres coated in a specialized synthetic polymer layer. When the automated separator activates its external magnetic field, this matrix amplifies the magnetic forces to capture micro-sized MACS® MicroBeads cleanly without crushing or stressing the cell bodies.\u003c\/li\u003e\n\u003cli\u003eAutomated High-Throughput Processing: Specifically engineered to fit the mechanical fluid paths and valve manifolds of the autoMACS® series. This integration enables fully automated multi-sample cell sorting loops that run safely without manual oversight.\u003c\/li\u003e\n\u003cli\u003eOptimized Hydrodynamic Flow Profiles: The uniform spacing between the matrix spheres allows unlabelled cells and structural debris to pass through freely while preventing nonspecific trapping, preserving exceptional downstream target cell purity.\u003c\/li\u003e\n\u003cli\u003ePre-Sterilized and Safe: Individually packed and sterilized using validated methods. This ensures the fluid paths remain completely free of external bio-burden, keeping primary tissue collections and downstream cell lines safe during isolation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eModel Number \/ Catalog No: 130-021-101 (autoMACS® Consumable Series)\u003c\/li\u003e\n\u003cli\u003ePrimary Manufacturer: Miltenyi Biotec® Inc.\u003c\/li\u003e\n\u003cli\u003eInstrument Compatibility: Benchtop autoMACS® and autoMACS® Pro Separator units\u003c\/li\u003e\n\u003cli\u003eSeparation Surface Chemistry: Non-toxic, hydrophilic polymer-coated ferromagnetic sphere bedding\u003c\/li\u003e\n\u003cli\u003eSterility Baseline: Certified Pre-Sterilized via radiation parameters\u003c\/li\u003e\n\u003cli\u003ePurity Verification: Non-pyrogenic, endotoxin-tested, and optimized to keep delicate primary cells highly viable\u003c\/li\u003e\n\u003cli\u003eMaximum Cell Sample Load: Optimized to process up to $2 \\times 10^8$ magnetically labeled cells or $2 \\times 10^9$ total cell inputs per automated column run\u003c\/li\u003e\n\u003cli\u003ePackaging Configuration: Pack of 8 Columns (Each column is safely sealed within a sterile convenience pouch)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003ePositive Target Selection: Ideal for isolating rare target populations, such as specific stem cell subsets, CD4+\/CD8+ T-lymphocytes, or dendritic cells, retaining them inside the matrix until demagnetization triggers elution.\u003c\/li\u003e\n\u003cli\u003eDepletion Sorting Routines: Highly effective at wiping away unwanted background cells—such as removing dead components or non-target erythrocytes—to yield a highly purified, unlabelled target fraction in the flow-through.\u003c\/li\u003e\n\u003cli\u003eOncology Stem Cell Isolation: Frequently integrated into cancer research tracks to isolate tumor-initiating cells or rare circulating tumor cells (CTCs) from dense tissue extractions or whole blood matrices.\u003c\/li\u003e\n\u003cli\u003eDownstream Genomic Validation: Delivering high-purity cells ensures clean results for downstream single-cell RNA sequencing (scRNA-seq), PCR analysis, flow cytometry profiling, or adoptive cell transfer assays.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eMiltenyi Biotec®, MACS®, and autoMACS® are registered commercial trademarks of Miltenyi Biotec B.V. \u0026amp; Co. KG. Catalog number 130-021-101 specifies the automated sterile column pack. For manual separation procedures utilizing static magnets, separate gravity-driven LS, MS, or LD column arrays must be substituted.\u003c\/small\u003e\u003c\/p\u003e","brand":"Miltenyi Biotec","offers":[{"title":"Default Title","offer_id":49219006071036,"sku":"10835","price":142.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/milenyi-biotec-automacs-column-sterile-pack-of-8-columns-chromatography-columns-reservoirs-miltenyi-biotec-377340.jpg?v=1782149532","url":"https:\/\/lifesciencestrading.com\/es\/products\/milenyi-biotec-automacs-column-sterile","provider":"Life Sciences Trading","version":"1.0","type":"link"}