Omni International Tough Tubes 2 ml Screw Cap Case of 500 Sample Tubes

Omni International 2 mL Reinforced Empty Tough Tubes with Screw Caps & EPDM O-Rings (19-648) – Case of 500

The Omni International 19-648 Tough Tubes are heavy-duty, molecular biology-grade sample vessels designed to withstand extreme mechanical forces during high-impact bead mill homogenization. Molded from reinforced, high-clarity polypropylene, these 2.0 mL skirted tubes are engineered specifically for use on the Omni Bead Ruptor 12, Bead Ruptor 24, and Bead Ruptor Elite platforms. Each tube features a secure polypropylene screw cap integrated with a high-performance synthetic EPDM O-ring, forming a leak-proof seal that prevents sample aerosolization and cross-contamination during intense multi-directional agitation. Supplied as an empty bulk case of 500 tubes and 500 caps, this configuration allows laboratories to customize their lysing matrices using distinct bead media for processing tough tissues, spores, or environmental matrices.

Technical Performance & Structural Integrity

• Impact-Resistant Polypropylene Architecture: Thickened, reinforced tube walls resist cracking and shearing at extreme mechanical frequencies (up to 8 m/s), eliminating tube failure during violent bead-to-sample collisions.
• Synthetic EPDM O-Ring Sealing: The cap is fitted with a specialized Ethylene Propylene Diene Monomer (EPDM) elastomer ring that provides superior sealing resilience over standard rubber, preventing fluid bypass under high kinetic pressure.
• Broad Thermal Range Tolerance: Chemically stable from $-80^\circ\text{C}$ to $121^\circ\text{C}$, making them fully compatible with cryogenic flash-freezing workflows, heat-induced lysis steps, or automated storage runs.
• Certified Nuclease-Free Purity: Evaluated to be strictly free of RNase and DNase contamination, ensuring absolute preservation of genomic DNA, total RNA, and protein analytes during energetic mechanical lysis.

Product Specifications

• Catalog Number / MPN: 19-648 (Alternative package sizes listed under 19-649)
• Primary Manufacturer: Omni International (A Revvity Company)
• Nominal Tube Capacity: 2.0 mL
• Functional Processing Range: 200 µL to 1.5 mL sample volume
• Physical Dimensions: 10.8 mm Outer Diameter x 44.0 mm Structural Length
• Material Profile: Reinforced Polypropylene (Tube body and screw cap) | High-Clarity Finish
• O-Ring Elastomer: Synthetic EPDM (Ethylene Propylene Diene Monomer)
• Maximum Centrifugation Rating: Verified up to 20,000 × g
• Base Design: Self-standing skirted bottom for single-handed bench manipulation
• Packaging Configuration: Case of 500 Empty Tubes and 500 Matching Screw Caps

Key Benefits & Applications

• Custom Lysing Matrix Development: Enables operators to batch-fill empty vessels with custom ratios of ceramic, glass, garnet, or metal bulk grinding beads tailored to unique laboratory cell-disruption protocols.
• Tough Micro-Organism and Tissue Lysis: Provides the rugged housing required to grind challenging matrices including Gram-positive bacteria, yeast cell walls, fungal spores, plant foliage, and fibrous animal tissue.
• Cryogenic Homogenization Prep: Withstands rapid temperature swings when transition-staged through pre-cooling blocks or the Bead Ruptor Cryo Cooling Unit without manifesting polymer brittleness.
• Elimination of Carryover Risks: The disposable, single-use format replaces reusable stainless steel generator probes or milling jars, completely removing the threat of sample-to-sample carryover in downstream PCR assays.

Omni International®, Bead Ruptor™, and Tough Tubes are active commercial trademarks of Omni International Inc. (Revvity). Catalog number 19-648 indicates the 500-pack reinforced empty 2 mL profile. For workflows requiring pre-loaded matrices, companion pre-filled bead beating tubes containing specialized ceramic, glass, or stainless steel matrices must be selected from the Omni product tree.