{"product_id":"repligen-midikros-hollow-fiber-filter-20-cm-length-0-2-um-pes-1-mm-fll-x-fll","title":"Repligen MidiKros Hollow Fiber Filter 20 cm Length 0.2 um PES 1 mm FLL X FLL","description":"\u003ch3\u003eRepligen MidiKros Hollow Fiber Filter, 20 cm Length, 0.2 µm mPES, 1.0 mm ID, FLL x FLL (P-D02-E20U-10-N)\u003c\/h3\u003e\n\u003cp\u003eThe Repligen MidiKros Hollow Fiber Filter (P-D02-E20U-10-N) is a high-performance single-use tangential flow filtration (TFF) module engineered for pilot-scale, benchtop, and clinical bioprocessing applications. Featuring a 0.2 µm sterilizing-grade pore size microfiltration membrane composed of modified Polyethersulfone (mPES), this filter delivers exceptional flux rates, low protein binding, and high volumetric throughput during bio-burden reduction, cell clarification, and particle separation workflows. Designed with a 20 cm active path length and a wide 1.0 mm lumen inner diameter (ID) fiber geometry, the module reduces fluid shear stress and accommodates higher viscosity fluids or higher cell density feeds. Encapsulated in a clear, biocompatible polysulfone housing with standard Female Luer Lock (FLL) process and permeate port connections, the MidiKros module seamlessly integrates into automated or manual TFF assemblies, enabling linear scale-up to larger bioprocess-scale filtration systems while eliminating cleaning validation and cross-contamination risks.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance \u0026amp; Structural Attributes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAdvanced mPES Membrane Chemistry: Hydrophilized modified Polyethersulfone provides minimal non-specific binding, excellent chemical tolerance across a broad pH range, and reduced membrane fouling during complex biological separations.\u003c\/li\u003e\n\u003cli\u003eWide 1.0 mm Lumen Diameter: High-clearance 1.0 mm inner diameter fibers reduce cross-flow shear stress on delicate cellular structures while preventing channel clogging from high-solids feeds.\u003c\/li\u003e\n\u003cli\u003eSingle-Use Encapsulated Design: Factory-assembled and potted in a USP Class VI housing, eliminating cartridge installation steps, system cleaning validation, and water-for-injection (WFI) pre-flushing requirements.\u003c\/li\u003e\n\u003cli\u003eStandardized Luer Lock Interface: Features Female Luer Lock (FLL) fittings on both process feed\/retentate flow paths and side permeate ports for fast, leak-free connection to flexible tubing circuits and sampling manifolds.\u003c\/li\u003e\n\u003cli\u003eLinear Bioprocess Scalability: Shares identical fluid channel height and membrane properties with larger KrosFlo and MaxiKros hollow fiber modules to ensure predictable performance during scale-up.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCatalog \/ Part Number: P-D02-E20U-10-N\u003c\/li\u003e\n\u003cli\u003ePrimary Manufacturer: Repligen Corporation\u003c\/li\u003e\n\u003cli\u003eFilter Module Series: MidiKros Hollow Fiber Module\u003c\/li\u003e\n\u003cli\u003eMembrane Material: Modified Polyethersulfone (mPES)\u003c\/li\u003e\n\u003cli\u003ePore Size Rating: 0.2 µm (Microfiltration \/ Bio-burden Reduction)\u003c\/li\u003e\n\u003cli\u003eFiber Inner Diameter (ID): 1.0 mm\u003c\/li\u003e\n\u003cli\u003eActive Module Path Length: 20 cm\u003c\/li\u003e\n\u003cli\u003eFeed \/ Retentate Connections: Female Luer Lock (FLL)\u003c\/li\u003e\n\u003cli\u003ePermeate Port Connections: Female Luer Lock (FLL)\u003c\/li\u003e\n\u003cli\u003eHousing Material: Polysulfone (PSU), USP Class VI Compliant\u003c\/li\u003e\n\u003cli\u003eRegulatory Compliance: USP Class VI, ISO 10993, Gamma Irradiated \/ Autoclavable, Non-Pyrogenic\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSterilizing Microfiltration \u0026amp; Bio-Burden Reduction: Provides effective removal of bacteria, cellular fragments, and particulate matter from culture broths and buffer solutions.\u003c\/li\u003e\n\u003cli\u003eCell Clarification \u0026amp; Bioreactor Harvesting: Ideal for continuous or batch harvesting of mammalian cells (CHO, HEK293) and plant cell cultures under low-shear fluidic conditions.\u003c\/li\u003e\n\u003cli\u003eViral Vector \u0026amp; Nanoparticle Concentration: Gently concentrates large biological complexes, adenovirus\/AAV vectors, liposomes, and cellular exosomes without altering particle integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eAll product names, logos, and brands are property of their respective owners. Repligen, MidiKros, KrosFlo, and MaxiKros are registered trademarks of Repligen Corporation.\u003c\/small\u003e\u003c\/p\u003e","brand":"Repligen","offers":[{"title":"Default Title","offer_id":67719661551868,"sku":"11020","price":190.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/repligen-midikros-hollow-fiber-filter-20-cm-length-02-um-pes-1-mm-fll-x-fll-filters-repligen-694974.jpg?v=1792096431","url":"https:\/\/lifesciencestrading.com\/es\/products\/repligen-midikros-hollow-fiber-filter-20-cm-length-0-2-um-pes-1-mm-fll-x-fll","provider":"Life Sciences Trading","version":"1.0","type":"link"}