Corning Costar 3690 Culture Microplate 96 Well EIA/RIA High Binding - 15 Microplates

Corning Costar 3690 96-Well Half-Area High Binding Microplate (EIA/RIA)

The Corning Costar 3690 is a precision-engineered 96-well microplate designed for high-sensitivity Immunoassays (EIA/RIA) where reagent conservation is a priority. Featuring a unique "Half-Area" well geometry, this plate allows researchers to reduce sample and reagent volumes by 50% while maintaining the standard path length of a 96-well format. The specialized High Binding surface is modified to enhance the adsorption of medium-to-large biomolecules (including IgG), ensuring superior coating efficiency and high signal-to-noise ratios. Manufactured from crystal-grade polystyrene, the 3690 is the ideal choice for high-throughput screening, antibody titrations, and diagnostic assay development.

Technical Performance and Design

• Half-Area Reagent Savings: The reduced well diameter allows for optimal performance with working volumes as low as 25 µl, significantly reducing the cost per well for expensive antibodies and rare samples.

• High Binding Surface Chemistry: The polystyrene surface is vacuum-gas plasma treated to increase its binding capacity for proteins and molecules with ionic groups or hydrophobic regions (400–500ng IgG/cm²).

• Exceptional Optical Clarity: The clear, flat-bottom design ensures a distortion-free optical path, making it fully compatible with standard top-reading and bottom-reading microplate readers.

• Standardized Footprint: Despite the half-area well design, the plate conforms to standard ANSI/SLAS dimensions, ensuring seamless integration with automated liquid handlers and robotic stackers.

Product Specifications

• Catalog Number: 3690

• Format: 96-Well Half-Area Clear Flat Bottom

• Surface Treatment: High Binding (Non-TC Treated)

• Total Well Volume: 190 µl

• Recommended Working Volume: 25 to 125 µl

• Growth/Binding Area: 0.158 cm² per well

• Sterility: Non-sterile (Standard for EIA/RIA assays)

• Packaging: 25 Plates per Bag / 100 Plates per Case

Key Benefits & Applications

• Cost-Efficient ELISA: Specifically designed for assays using high-value reagents where reducing volume from 100 µl to 50 µl provides significant long-term savings.

• Maximized Signal Intensity: The narrow well diameter increases the concentration of the analyte over the binding surface, often leading to improved sensitivity in colorimetric assays.

• Diagnostic Assay Development: Used extensively in the development of commercial assay kits requiring high reproducibility and well-to-well consistency.

• Ease of Automation: The rigid sidewall construction and standard footprint prevent warping and ensure reliable performance during vigorous automated washing and shaking cycles.

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