Repligen MiniKros Hollow Fiber Filter Sterile 750 kDa Sanitary Fittings

The Repligen MiniKros Hollow Fiber Filter, specifically model S02-E750-05-N, is a sterile filtration device designed for bioprocessing applications requiring efficient separation and purification of biomolecules. This filter is characterized by its hollow fiber design, a technology that provides a large surface area for filtration within a compact unit, leading to enhanced processing efficiency.

The filter utilizes a modified polyethersulfone (mPES) membrane with a 750 kDa (kilodalton) molecular weight cutoff (MWCO). This MWCO is crucial, as it determines the size of molecules retained by the filter, making it suitable for separating proteins, antibodies, and other biomolecules from smaller substances. The filter's 1600 cm² filtration area allows for processing significant volumes of liquid, making it suitable for laboratory-scale and process development applications. The inclusion of sanitary fittings ensures compatibility with bioprocessing equipment and facilitates aseptic connections, maintaining the sterility of the process.

This Repligen MiniKros Hollow Fiber Filter is a valuable tool for biopharmaceutical manufacturers and researchers needing reliable and sterile filtration for applications like protein concentration, diafiltration (buffer exchange), and clarification.