{"product_id":"biotage-microplate-isolute-sle-plus-200-ul96-well-sealed-plates","title":"Biotage Filter Microplate Isolute SLE Plus 200 ul 96 Well 2 Plates","description":"\u003ch3\u003eBiotage ISOLUTE SLE+ Supported Liquid Extraction Plate – 200 µL, 96-Well\u003c\/h3\u003e\n\u003cp\u003eThe Biotage 800-0200-P01 is a highly advanced Supported Liquid Extraction (SLE) microplate designed to deliver the high-purity analyte recoveries of traditional liquid-liquid extraction (LLE) without the associated manual labor and phase-separation bottlenecks. Each well in the 96-well manifold is optimized to process aqueous sample volumes up to 200 µL. The plate utilizes ISOLUTE SLE+, a highly modified, wide-pore diatomaceous earth sorbent that acts as a physical support for the aqueous matrix. By spreading the biological sample thinly over the massive surface area of the sorbent, the subsequent application of an organic elution solvent results in highly efficient, thermodynamically optimized analyte partitioning. This seamless \"load-wait-elute\" workflow provides exceptional reproducibility and completely bypasses the need for vigorous shaking, centrifugation, and manual pipetting of organic layers.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eEmulsion-Free Extraction:\u003c\/b\u003e By immobilizing the aqueous phase on a solid diatomaceous earth support, the SLE+ phase completely prevents the formation of unbreakable protein emulsions that frequently ruin traditional liquid-liquid extractions.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh Surface Area Partitioning:\u003c\/b\u003e The microporous structure of the solid support spreads the 200 µL sample into an ultra-thin film, maximizing the contact area with the organic extraction solvent to ensure near-100% recovery of neutral, acidic, and basic analytes.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSimplified Load-and-Elute Workflow:\u003c\/b\u003e Eliminates the tedious off-line capping, vortexing, and centrifuge steps. The sample is loaded, allowed 5 minutes to absorb, and then eluted directly with a water-immiscible organic solvent (like MTBE, ethyl acetate, or hexane).\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh-Throughput 96-Well Format:\u003c\/b\u003e Built into a standard SBS-footprint polypropylene plate, making it seamlessly compatible with automated liquid handling robots and positive pressure manifolds for rapid batch processing.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 800-0200-P01\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFormat:\u003c\/b\u003e 96-Well Fixed Plate\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePhase\/Chemistry:\u003c\/b\u003e ISOLUTE SLE+ (Modified Diatomaceous Earth)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaximum Sample Volume:\u003c\/b\u003e 200 µL per well\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHousing Material:\u003c\/b\u003e Polypropylene\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTarget Extraction:\u003c\/b\u003e Supported Liquid Extraction (Alternative to LLE)\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eClinical \u0026amp; Forensic Toxicology:\u003c\/b\u003e The absolute gold standard for the high-throughput extraction of pain management panels, drugs of abuse, steroids, and hormones from human plasma, serum, and urine.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLC-MS\/MS Optimization:\u003c\/b\u003e Consistently yields exceptionally clean extracts that are free of ion-suppressing proteins and phospholipids, significantly extending the lifespan of sensitive mass spectrometry detectors.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSolvent Reduction:\u003c\/b\u003e Uses drastically less organic solvent than traditional LLE in test tubes, lowering consumable costs and reducing hazardous chemical waste in the laboratory.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eAutomated Scalability:\u003c\/b\u003e Perfectly translates difficult, manual shake-flask chemistry into a fully automatable plate-based format, easily doubling or tripling daily laboratory throughput.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Biotage","offers":[{"title":"Default Title","offer_id":44789843296508,"sku":"6025","price":52.25,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/biotage-microplate-isolute-sle-plus-200-ul96-well-2-sealed-plates-filters-biotage-108414.jpg?v=1713475951","url":"https:\/\/lifesciencestrading.com\/products\/biotage-microplate-isolute-sle-plus-200-ul96-well-sealed-plates","provider":"Life Sciences Trading","version":"1.0","type":"link"}