Charter Medical Biocube 2L with Clear Pak Film Set of 2 Bags

Charter Medical BioCube Single-Use Flexible Bio-Container – 2 L Volume, Clear-Pak Multi-Layer Film, Self-Supporting Aseptic Storage Design (MPN: CML-BIOCUBE-2L)

The Charter Medical CML-BIOCUBE-2L is a premium, single-use flexible bioprocessing container designed for the safe handling, transport, and cold storage of critical sterile fluids, cell culture media, and downstream biopharmaceutical intermediates. Engineered with a unique, self-supporting dimensional geometry, this 2 Liter flexible liner bag eliminates the absolute necessity of rigid secondary outer support buckets during active fluid fills. Fabricated from proprietary Clear-Pak multi-layer co-extruded film, the container pairs an inert Ultra-Low Density Polyethylene (ULDPE) contact layer with an Ethylene Vinyl Alcohol (EVOH) gas barrier. This robust structural barrier provides exceptional optical clarity, structural strength, and protection against gas transmission while functioning flawlessly across an extensive thermal operating horizon.

Technical Performance and Design

• Self-Supporting BioCube Architecture: Developed with an innovative physical structure that expands into a stable, freestanding footprint as fluid fills the cavity. This design simplifies handling on laminar flow hoods and bench spaces, optimizing space efficiency inside deep freezers and cold storage vaults.

• Clear-Pak Multi-Layer Co-Extruded Film: Formulated with a high-performance single web film system consisting of an outer Polyethylene (PE) durability shell, an intermediate EVOH gas barrier layer, and an ultra-pure ULDPE fluid contact liner. This multi-layer approach ensures superior flexibility and mechanical tear resistance.

• Advanced EVOH Gas Barrier Layer: Incorporates an Ethylene Vinyl Alcohol (EVOH) core barrier that restricts oxygen and carbon dioxide transmission. This feature prevents pH drift and oxidation, safeguarding the chemical stability of sensitive biological reagents and cell culture medias over long storage periods.

• Extensive Cryogenic Operating Horizon: The specialized polymer matrix retains its physical pliability and impact strength without fracturing or embrittlement across a wide thermal operating range, safely weathering deep frozen archiving down to minus 80°C (-80°C).

Product Specifications

• Catalog Number / MPN: CML-BIOCUBE-2L (BioCube Series)

• Manufacturer / Brand: Charter Medical, Ltd.

• Nominal Storage Capacity: 2 Liters (2L)

• Film Technology Substrate: Clear-Pak Co-Extruded Polymer (13 mil / 330 micron thickness)

• Fluid Contact Material: Ultra-Low Density Polyethylene (ULDPE) — Animal Derivative Component Free (ADCF)

• Gas Barrier Efficiency: Oxygen transmission rate of less than 0.003 mL/100 sq. in./day/atm

• Thermal Endurance Window: Rated for safe physical operation from minus 80°C up to plus 50°C

• Regulatory Compliance Standards: USP Class VI Biocompatibility Pass, USP <87> Cytotoxicity Pass, USP <85> Bacterial Endotoxin Pass, and ISO 13485 certified cleanroom manufacturing

• Standard Case Configuration: Wholesale box containing 20 individual bio-container assemblies

Key Benefits and Applications

• Biopharma Media and Buffer Storage: The single-use cleanroom choice for holding sterile fluid lots, intermediate cell harvest fractions, purification buffers, and process reagents without cross-contamination risks.

• Aseptic Media Fill Applications: Deployed alongside large-scale cell expansion loops and bioreactor networks to manage process fluids during sterile scale-up workflows.

• Optical Process Clarity: Features a 97 percent clarity and 93 percent light transmittance rating, allowing technicians to easily perform visual inspections for color changes, particulate matter, or precipitate formation.

• Eliminated Cleaning Validation Costs: The disposable, single-use format removes the need for capital-intensive Clean-in-Place (CIP) and Steam-in-Place (SIP) validation cycles, reducing turnaround times between production batches.

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