Corning Microplate with Lid 96 Well Flat Bottom Polystyrene Individually Sealed Case of 50 Plates

Corning® Costar® 96-Well Clear Flat-Bottom Tissue Culture-Treated Microplates with Lids (3595) – Case of 50

The Corning® Costar® 3595 is a gold-standard, research-grade multi-well consumable engineered for high-throughput screening, downstream cell culture scaling, ELISA assays, and automated optical profiling. Injection-molded from premium, high-purity virgin polystyrene, each plate features a standard 96-well matrix with optical flat-bottom wells that eliminate light scattering and optical distortion during inverted microscopic analysis. The interior growth surface of each individual well undergoes a standardized, vacuum-gas plasma tissue culture (TC) treatment, introducing hydrophilic oxygen functional groups to maximize cell attachment, spreading, and replication stability. Supplied as a commercial case of 50 individually paper-plastic peel-wrapped plates with matching lids, this model ensures strict aseptic barriers for clinical, diagnostic, and academic research installations.

Technical Performance & Design Architecture

• Vacuum-Plasma Surface Treatment: The surface modification process converts the hydrophobic polystyrene base into a uniform hydrophilic substrate. This permanent treatment promotes reliable cell adhesion and division across all 96 wells, suppressing variable well-to-well cell cluster mapping.
• Condensation-Control Non-Reversible Lid: The included clear polystyrene lid incorporates a non-reversible layout paired with dedicated condensation rings matching the 96-well matrix. This design ensures safe gas exchange while minimizing evaporation rates and preventing aerosol drop-drift contamination across adjacent wells.
• Aseptic Peel-Pack Isolation: Every multi-well plate is packed individually in a medical-grade paper/plastic blister pouch. This allows operators to easily peel open the packaging and transfer the sterile unit into a laminar flow biosafety cabinet without introducing ambient laboratory dust or debris.
• Molded Alphanumeric Tracking Coordinates: Features high-contrast, raised alphanumeric labeling (Rows A–H, Columns 1–12) around each well rim. This tracking layout simplifies rapid sample identification during manual loading loops and facilitates liquid handling automation teaching steps.

Product Specifications

• Catalog Number / MPN: 3595 (Costar® Product Family)
• Primary Manufacturer: Corning Life Sciences
• Plate Format Configuration: 96-Well Multi-Well Matrix (8 x 12 Array)
• Well Bottom Profile: Flat-Bottom Geometry (Optimized for microscopy and high-resolution inverted cell scanning)
• Surface Chemistry: Standard Tissue Culture (TC) Treated (Hydrophilic surface profile)
• Material Composition: Optical-grade, USP Class VI virgin polystyrene (Latex-free / Silicone-free)
• Total Well Volume Capacity: Nominal 360 µL per well
• Recommended Working Volume: 75 µL to 200 µL per well
• Cell Growth Area: Nominal 0.32 cm² per well
• Sterility & Purity Status: Gamma-irradiation sterilized; Certified Non-Pyrogenic and Non-Cytotoxic
• Packaging Configuration: Case of 50 Plates with Lids (Individually wrapped and nested within space-saving master warehouse cartons)

Key Benefits & Applications

• High-Throughput Cell Dosing and Cytotoxicity Assays: The ideal structural tool for running automated drug screening, cell viability panels (e.g., MTT or CCK-8), and transfection optimization assays.
• High-Resolution Inverted Microscopy: Precision injection-molded flat well bases provide a uniform, thin optical window, delivering crisp, distortion-free focal planes during fluorescence or phase-contrast monitoring.
• Automation and Robotic Stacking: Built to meet universal ANSI/SLAS footprint standard specifications, ensuring smooth, jam-free physical integration with automated microplate washers, multi-channel electronic pipettors, and robotic incubator tracks.
• **Lot-Specific Compliance Tracking:** Each individual sterile pouch has the master manufacturing lot code and expiration metric printed directly on the exterior liner to facilitate cleanroom auditing and institutional inventory compliance.

Corning® and Costar® are registered commercial trademarks of Corning, Inc. Catalog number 3595 specifies the clear, flat-bottom, TC-treated 96-well setup provided with a lid. For specialized suspension cells or specialized assays where cell attachment must be blocked or alternative surfaces are required, companion Ultra-Low Attachment (ULA) or CellBIND® multi-well configurations should be cross-referenced within the procurement system.