{"product_id":"corning-4513-culture-plates-384-well-low-volume-round-bottom-sealed","title":"Corning Culture Plates 384 Well Low Volume Round Bottom Sealed Case of 50 Plates","description":"\u003ch3\u003eCorning 384-Well Low Volume Solid White Round Bottom NBS Microplates, Non-Sterile (4513) – Case of 50\u003c\/h3\u003e\n\u003cp\u003eThe Corning 384-Well Low Volume White Microplates with Nonbinding Surface (4513) are specialized, high-density assay plates engineered for miniaturized homogeneous assays, fluorescence\/luminescence screening, and low-concentration target binding studies. Constructed from solid white polystyrene, these microplates feature a light cone-shaped conical well geometry with round bottoms, which minimizes trapped air bubbles, lowers working volume requirements, and enhances the overall Z-factor for high-throughput screening (HTS). Treated with Corning’s proprietary Nonbinding Surface (NBS) technology, the nonionic hydrophilic surface prevents non-specific protein and nucleic acid adsorption to well walls. Supplied as a case of 50 non-sterile plates (packaged as 5 inner bags of 10 plates each, without lids), this consumable line delivers high signal-to-noise performance for automated biochemical assays.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance \u0026amp; Key Attributes\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eProprietary Nonbinding Surface (NBS) Treatment: Creates a nonionic hydrophilic surface (polyethylene oxide-like) that reduces molecular interactions and prevents non-specific binding of proteins and DNA\/RNA at low concentrations.\u003c\/li\u003e\n\u003cli\u003eMiniaturized Low Volume Geometry: Conical light-cone well design with a round bottom allows a recommended working volume of just 5 µL to 40 µL, conserving costly reagents while maximizing assay signal efficiency.\u003c\/li\u003e\n\u003cli\u003eSolid White Opaque Walls: Reflects emitted light signals to boost luminescent intensity while eliminating well-to-well crosstalk and background autofluorescence.\u003c\/li\u003e\n\u003cli\u003eRobotic Pipetting Efficiency: Features a square well top profile that increases the target opening area for automated liquid handling tips and multi-channel dispensers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eCatalog Number \/ MPN: 4513 (Suggested replacement for Corning 3673)\u003c\/li\u003e\n\u003cli\u003ePrimary Manufacturer: Corning Life Sciences\u003c\/li\u003e\n\u003cli\u003ePlate Format: 384-Well Low Volume Microplate (16 x 24 Array)\u003c\/li\u003e\n\u003cli\u003eWell Shape \u0026amp; Bottom Profile: Square Top with Round \/ Conical Bottom (U-Bottom)\u003c\/li\u003e\n\u003cli\u003eTotal Well Volume: 50 µL per well\u003c\/li\u003e\n\u003cli\u003eRecommended Working Volume: 5 µL to 40 µL per well\u003c\/li\u003e\n\u003cli\u003eMaterial Composition: Optical-Grade Solid White Polystyrene (PS)\u003c\/li\u003e\n\u003cli\u003eSurface Treatment Status: Nonbinding Surface (NBS) Treatment\u003c\/li\u003e\n\u003cli\u003eSterility Status: Non-Sterile\u003c\/li\u003e\n\u003cli\u003eLid Status: Supplied without lids\u003c\/li\u003e\n\u003cli\u003ePackaging Configuration: Case of 50 microplates (5 inner bags x 10 plates per bag)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHigh-Throughput Screening (HTS): Optimized for miniaturized fluorometric, luminescent, and homogeneous proximity assays (e.g., LANCE, AlphaScreen, and TR-FRET).\u003c\/li\u003e\n\u003cli\u003eLow Concentration Target Protection: NBS treatment prevents target biomolecules from sticking to plastic walls, enhancing signal-to-noise ratios in delicate binding kinetics.\u003c\/li\u003e\n\u003cli\u003eReagent Savings: Low working volume range (5–40 µL) dramatically reduces enzyme, fluorophore, and substrate consumption during large-scale library screens.\u003c\/li\u003e\n\u003cli\u003eAutomated Handling Fit: Conforms to standard ANSI\/SLAS microplate dimensions for seamless integration into robotic grippers, plate washers, and readers.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr\u003e\n\u003cp\u003e\u003csmall\u003eAll product names, logos, and brands are property of their respective owners. Corning is a registered trademark of Corning Incorporated.\u003c\/small\u003e\u003c\/p\u003e","brand":"Corning","offers":[{"title":"Default Title","offer_id":44498086887676,"sku":"1588","price":332.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/IMG_4991_Shopify1024.jpg?v=1785945349","url":"https:\/\/lifesciencestrading.com\/products\/corning-4513-culture-plates-384-well-low-volume-round-bottom-sealed","provider":"Life Sciences Trading","version":"1.0","type":"link"}