Corning Axygen Microplate Sealing Film 100 Seals

Corning Axygen MF-300 Microplate Heat Sealing Film – Paper Backed, Clear

The Corning Axygen MF-300 is a high-performance, clear heat-sealing film engineered for the permanent, leak-proof closure of microplates and PCR plates. Designed for use with automated and semi-automated heat sealing instruments, this film provides an exceptional hermetic seal that eliminates evaporation and well-to-well cross-contamination, even during high-temperature thermal cycling or long-term cryogenic storage. The film features a specialized paper-backed carrier that maintains structural rigidity and protects the sealing surface from dust and fingerprints prior to application. Manufactured from high-clarity polyester, the MF-300 allows for easy visual inspection of samples and is compatible with optical plate readers. Once heat-applied, it forms a secure bond with polypropylene plates that can only be removed by peeling (if using a peelable version) or piercing, ensuring maximum sample integrity for sensitive molecular biology applications.

Technical Performance and Design

• Permanent Hermetic Seal: Creates a continuous fusion with the plate rim, providing a superior barrier against moisture loss compared to standard adhesive films, making it ideal for low-volume PCR and long-term archiving.

• Paper-Backed Carrier: The integrated paper backing ensures the film remains perfectly flat during the loading process, preventing jams in automated sealers and ensuring a uniform seal across all 96 or 384 wells.

• Wide Thermal Range: Specifically formulated to withstand the extreme temperature fluctuations of PCR (-20°C to 110°C) and ultra-low temperature freezer storage (-80°C) without losing seal integrity.

• High Optical Clarity: The ultra-clear polyester material allows for precise fluorescent detection and visual sample verification without the need to remove the seal.

Product Specifications

• Catalog Number: MF-300 (Corning / Axygen)

• Format: Sheet (Individual sheets with paper backing)

• Sealing Method: Heat Sealer Required

• Material: Clear Polyester

• Dimensions: Standard Microplate Footprint (Approx. 125 x 78 mm)

• Quantity: Typically sold in packs of 100 sheets

Key Benefits & Applications

• PCR & qPCR: Prevents the "edge effect" and evaporation-driven concentration shifts in 96-well and 384-well thermal cycling, ensuring reproducible results in sensitive amplification assays.

• Long-Term Sample Archiving: Provides a highly durable, airtight barrier for compound libraries and DNA banks stored in deep-well polypropylene plates.

• Automation Compatibility: Designed to work seamlessly with leading heat sealers such as the Agilent PlateLoc, Brooks/Azo, and Axygen PlateMax systems.

• Chemical Resistance: Resistant to commonly used laboratory solvents, including 100% DMSO, making it suitable for drug discovery and high-throughput screening workflows.

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