Corning 430776 Centrifuge Tubes 250 ml Plug Seal Cap Sterile Case of 102

Corning 430776 250 ml Centrifuge Tubes (Sterile, Plug Seal Cap)

The Corning 430776 is a high-capacity centrifuge vessel designed for the processing of large volumes of cell cultures, lysates, and reagents. Manufactured from medical-grade, high-clarity polypropylene, these 250 ml tubes offer the chemical resistance and structural integrity required for demanding laboratory applications. Featuring a specialized HDPE Plug Seal Cap, these tubes provide a reliable, leak-proof barrier even during high-speed centrifugation. Each tube is gamma-irradiated to ensure sterility and is certified non-pyrogenic, making them ideal for biopharmaceutical production and sensitive biological research.

Technical Performance and Design

• High-Capacity Processing: The 250 ml volume is optimized for large-scale cell harvesting, pelleting, and protein purification workflows that exceed the capacity of standard 50 ml conical tubes.

• Plug Seal Cap Technology: The high-density polyethylene (HDPE) cap is designed with a deep-seated plug that creates a multi-point friction seal against the inner wall of the tube, ensuring a liquid-tight and gas-tight closure.

• Superior Chemical Resistance: Polypropylene construction provides excellent compatibility with a wide range of laboratory solvents, alcohols, and acids, and allows for use in cold storage or heated water baths.

• Precision Molded Graduation: Features easy-to-read, molded-in graduations to facilitate accurate volume measurement and sample tracking during large-scale liquid handling.

Product Specifications

• Catalog Number: 430776

• Capacity: 250 ml

• Material: Polypropylene (Tube) / HDPE (Cap)

• Max RCF: 6,000 x g (Note: Must be used with appropriate rotor cushions/adapters)

• Sterility: Sterile (Gamma Irradiated); Non-pyrogenic

• Packaging: 6 Tubes per Bag / 102 Tubes per Case

• Dimensions: Approx. 60 mm (OD) x 158 mm (Length)

Key Benefits & Applications

• Bioprocessing & Scale-Up: Ideal for harvesting cells from large-scale fermenters or bioreactors and for the initial stages of downstream processing.

• Large Volume Storage: The sterile, leak-proof design makes these tubes excellent for storing bulk buffers, media, or chemical reagents in a stable, upright format.

• Reliable Durability: Engineered with thick-walled construction to withstand the mechanical stresses of high-speed centrifugation without cracking or leaking.

• Verified Purity: Certified to be free of DNase, RNase, and endotoxins, ensuring the integrity of sensitive genomic and proteomic samples.

Usage Requirement

To ensure safety and performance, these 250 ml tubes must be used with appropriate centrifuge rotor cushions or adapters (e.g., Corning 430236) to prevent tube failure during operation at maximum RCF.

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