Corning Erlenmeyer Flask 2L with Vent Cap Baffled Polycarbonate Case of 6 Flasks

Corning 2 L Baffled Polycarbonate Erlenmeyer Flask with Vent Cap (431256)

The Corning 431256 is a premium 2-liter Erlenmeyer flask engineered specifically for high-yield suspension cultures and aerobic fermentations. Manufactured from optically clear, medical-grade polycarbonate, this flask features a triple-baffled bottom designed to maximize oxygen transfer by increasing turbulence and surface area during agitation. The included 43 mm vent cap incorporates a 0.2 µm hydrophobic membrane, allowing for continuous, sterile gas exchange while preventing contamination and liquid leakage. With its shatter-proof construction and molded-in graduations, the 431256 offers a safer and more efficient alternative to traditional glass vessels, making it the industry standard for protein expression, vaccine development, and scale-up studies in orbital shakers.

Technical Performance and Design

• Triple-Baffled Bottom: The molded-in baffles disrupt laminar flow during shaking, significantly enhancing aeration and gas-liquid mass transfer, which is critical for the growth of oxygen-demanding microorganisms.

• Hydrophobic Vent Cap: The integrated 0.2 µm pore size membrane ensures a consistent supply of oxygen and CO2 while providing a reliable sterile barrier against airborne contaminants.

• Superior Mechanical Strength: Constructed from high-impact polycarbonate, this flask is designed to withstand the physical stresses of high-speed orbital shaking without the risk of shattering associated with glass.

• Optical Clarity: Glass-like transparency allows for easy visual monitoring of culture turbidity, color changes, and the presence of precipitates or contamination.

Product Specifications

• Catalog Number: 431256

• Capacity: 2 Liters (2000 ml)

• Base Style: Baffled Bottom

• Cap Style: 43 mm Vent Cap (0.2 µm Membrane)

• Material: Polycarbonate (Flask); High-Density Polyethylene (Cap)

• Sterility: Sterile (Gamma Irradiated to SAL 10^-6)

• Purity: Certified Non-Pyrogenic and Non-Cytotoxic.

• Graduations: Molded-in at 200 ml increments.

Key Benefits & Applications

• Aerobic Fermentation: Ideal for culturing E. coli, yeast, and other aerobic organisms that require high dissolved oxygen levels for optimal protein expression.

• Cell Culture Scale-Up: Provides a reliable environment for transitioning suspension-adapted mammalian or insect cells from small-scale tubes to pilot production.

• Aseptic Gas Exchange: The vent cap eliminates the need to "loosen" caps for aeration, maintaining a completely closed, sterile system during incubation.

• Single-Use Convenience: Delivered sterile and ready-to-use, eliminating the time and costs associated with washing, autoclaving, and validating reusable glassware.

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