Corning Erlenmeyer Flask 5 L with Vent Cap Fernbach Design Polycarbonate Lot of 3 Flasks

Corning 431685 Erlenmeyer Flask – 5 L, Fernbach Design, Polycarbonate, Sterile

The Corning 431685 is a high-capacity 5-liter Fernbach-style Erlenmeyer flask designed for large-scale cell culture and aerobic fermentation. Manufactured from high-clarity, medical-grade polycarbonate (PC), this flask offers the optical transparency of glass combined with superior shatterproof safety. The wide-bottom Fernbach geometry is specifically engineered to increase the liquid surface area, significantly enhancing oxygen transfer and gas exchange during orbital shaking. Supplied sterile and certified non-pyrogenic, the 431685 features a 70 mm vent cap with a 0.2 µm hydrophobic membrane, making it an ideal choice for seed train expansion, protein expression, and the cultivation of high-density suspension cell lines.

Technical Performance and Design

• Fernbach Wide-Base Geometry: The specialized wide footprint maximizes the surface area of the culture media, promoting superior aeration and nutrient distribution compared to traditional narrow-base flasks.

• 70 mm Vented Screw Cap: Equipped with a large-diameter cap containing a 0.2 µm hydrophobic membrane. This allows for continuous, sterile gas exchange while providing a secure microbial barrier against contamination.

• High-Clarity Polycarbonate: Constructed from USP Class VI polycarbonate, which is exceptionally durable and impact-resistant, ensuring safety during high-speed shaking and transport.

• Molded-in Graduations: Features permanent, easy-to-read volume markings for accurate media additions and monitoring of culture levels.

Product Specifications

• Catalog Number: 431685

• Capacity: 5 Liters

• Flask Style: Fernbach (Wide-Base)

• Material: Polycarbonate (USP Class VI)

• Closure Type: 70 mm Vented Cap (0.2 µm membrane)

• Sterility: Sterile (Gamma Irradiated, SAL 10⁻⁶)

• Certification: Certified Non-pyrogenic and RNase/DNase-free.

Key Benefits & Applications

• Large-Scale Aerobic Culture: Optimized for the growth of yeast, bacteria, and suspension mammalian cells that require high levels of oxygenation to reach peak densities.

• Bioprocess Scale-Up: A critical component for seed train expansion, bridging the gap between bench-scale R&D and pilot-scale bioreactor inoculation.

• Risk Mitigation: The disposable, single-use format eliminates the risk of cross-contamination and the overhead costs of cleaning and sterilization validation associated with glass vessels.

• Shatterproof Safety: Provides essential protection for personnel and high-value research by eliminating the risk of catastrophic glass breakage during high-volume shaking.

Expiration Date: 2021-01-17.

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