Corning Microplate 12 Well BioCoat with Lid TC Treated 50 Plates

Corning 356500 BioCoat Microplate – 12-Well, TC-Treated, with Lid, Sterile

The Corning 356500 BioCoat 12-well plate is a versatile and reliable solution for a wide range of cell culture applications. Manufactured from medical-grade, high-clarity polystyrene, this plate is surface-modified with a standardized Tissue Culture (TC) treatment to enhance cell attachment and proliferation. The BioCoat process ensures a highly uniform surface chemistry, reducing experimental variability and providing a stable foundation for the cultivation of primary cells and established cell lines. Each plate features a clear, flat-bottom well design for optimal microscopic visualization and is supplied with a custom-fit, low-evaporation lid to maintain aseptic conditions during long-term incubation.

Technical Performance and Design

• Uniform TC-Treated Surface: The surface is vacuum-gas plasma treated to create a hydrophilic and ionic environment, promoting the uniform attachment and spreading of anchorage-dependent cell types.

• Exceptional Optical Clarity: Constructed from premium polystyrene with a flat-bottom well geometry, ensuring distortion-free light paths for high-resolution imaging and colorimetric assays.

• Engineered Low-Evaporation Lid: Includes a non-reversible lid with condensation rings that align with each well to minimize media loss and protect against cross-contamination while facilitating consistent gas exchange.

• Alpha-Numeric Indexing: Features molded-in coordinates for each well, allowing for rapid sample identification and simplifying the tracking of complex experimental layouts.

Product Specifications

• Catalog Number: 356500

• Format: 12-Well Plate

• Surface Treatment: Standard Tissue Culture (TC) Treated

• Material: High-Clarity Polystyrene (USP Class VI)

• Growth Area: 3.8 cm² per well (approximate)

• Sterility: Sterile (Gamma Irradiated)

• Purity: Certified Non-pyrogenic and Non-cytotoxic.

Key Benefits & Applications

• General Cell Culture: The standard choice for routine maintenance and expansion of common cell lines (e.g., HeLa, CHO, 3T3) where consistent attachment is required.

• Transfection & Transduction: Provides the surface stability needed for cells to recover and thrive following the introduction of genetic material or viral vectors.

• Assay Scale-Down: The 12-well format offers a larger growth area than 96-well plates, making it ideal for experiments requiring higher cell yields for protein or RNA extraction.

• Microscopic Analysis: The flat, clear bottom is perfectly suited for phase-contrast and fluorescence microscopy, allowing for detailed observation of cell morphology and health.

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