Corning Microplate 96 Well 500 ul V Bottom PP 65 Plates

Corning 3957 Microplate – 96-Well, 500 µL, V-Bottom, Polypropylene

The Corning 3957 is a premium 96-well microplate engineered for high-throughput screening, sample collection, and long-term storage. Constructed from medical-grade, high-purity polypropylene, this plate offers exceptional chemical resistance against aggressive solvents like DMSO, ethanol, and methanol. Each well features a 500 µL working volume and a specialized V-bottom (conical) geometry, which is essential for maximum sample recovery and the precise aspiration of small volumes. The standardized SBS footprint ensures seamless compatibility with automated liquid handling systems, robotic grippers, and plate centrifuges. Supplied non-sterile and without lids, the 3957 is a robust, chemically inert solution for compound library management, protein purification, and any laboratory workflow requiring high-integrity sample containment.

Technical Performance and Design

• V-Bottom (Conical) Geometry: Designed specifically for total sample recovery; the tapered bottom directs liquids to a centralized point, minimizing dead volume during manual or automated pipetting.

• Polypropylene Construction: Provides superior thermal stability, allowing the plate to be frozen to -80°C for long-term archiving or autoclaved for decontamination.

• Standard SBS Footprint: Fully compliant with industry standards for microplates, ensuring 100% compatibility with automated workstations from manufacturers such as Hamilton, Tecan, and Agilent.

• Raised Well Rims: Specifically engineered to enhance the effectiveness of heat-sealing films or adhesive mats, providing a secure barrier against cross-contamination and sample evaporation.

Product Specifications

• Catalog Number: 3957

• Well Count: 96 Wells

• Total Volume: 500 µL per well

• Material: High-Purity Polypropylene (PP)

• Well Shape: V-Bottom (Conical)

• Sterility: Non-Sterile

Key Benefits & Applications

• Compound Library Storage: The DMSO-resistant nature of polypropylene ensures that small molecule collections remain stable and free from plasticizer leaching during long-term storage.

• Genomic Sample Preparation: Ideal for DNA/RNA extraction and purification protocols where chemical resistance to lysis buffers and alcohols is mandatory.

• Sample Concentration: The V-bottom design is highly effective for concentrating samples or resuspending pellets, as the concentrated material collects at the very bottom of the conical well.

• Space Optimization: The 500 µL profile allows for higher density in freezer racks compared to larger deep-well blocks, maximizing high-value cold storage space.

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