Corning Microplate 96 Well Strip Well Polystyrene 100 Plates

Corning 2485 Stripwell Microplate – 96-Well, White, High Bind, Low Volume

The Corning 2485 is a 96-well Stripwell microplate engineered for in vitro diagnostic assays and high-sensitivity immunoassays. Manufactured from solid white polystyrene, the plate consists of twelve 1x8 flat-bottom strips pre-assembled in a secure, "egg-crate" style holder. A defining physical characteristic of the 2485 is its low-volume, half-area well geometry, which significantly increases the surface-to-volume ratio compared to standard wells. The polymer undergoes a High Bind surface treatment to maximize the adsorption of proteins and large biomolecules. Optimized specifically for luminescence-based applications, this non-sterile plate is designed to minimize reagent consumption while providing maximum assay flexibility.

Technical Performance and Design

• High Binding Surface: The treated polystyrene binds medium to large biomolecules (>10 kD) that possess ionic groups or hydrophobic regions, providing a binding capacity of approximately 400 to 500 ng IgG/cm².

• Half-Area Low Volume Geometry: The unique round wells with flat, half-area bottoms hold a maximum of 190 µL. This reduces the required working volume to just 50–125 µL, drastically cutting expensive antibody and biological sample consumption.

• Luminescence Optimization: The opaque white polystyrene construction actively enhances luminescent signals while completely blocking well-to-well optical crosstalk and preventing background fluorescence.

• Break-Apart Stripwell Format: The 1x8 strips can be easily snapped apart to run partial assays, ensuring zero wasted wells. The holder's asymmetric design forces the strips to fit in only one direction, eliminating orientation errors.

Product Specifications

• Catalog Number: 2485

• Format: 96-Well Stripwell (Twelve 1x8 Strips)

• Material: Solid White Polystyrene

• Well Geometry: Round with Half-Area Flat Bottom

• Working Volume: 50 to 125 µL (190 µL Maximum)

• Surface Treatment: High Bind

• Sterility: Non-Sterile (Without Lid)

Key Benefits & Applications

• Luminescent Immunoassays: The absolute standard for running strict ELISA protocols or luciferase reporter assays where optical isolation and high protein retention are required.

• Reagent Conservation: The half-area bottom allows researchers to achieve the exact same optical pathlength and assay sensitivity as a standard plate while using significantly less reagent.

• Assay Flexibility: Ideal for clinical or low-throughput academic labs that only need to run a few samples at a time, completely avoiding the waste of using an entire solid 96-well plate.

• Automation Compatible: The fully assembled frame conforms to standard SBS/ANSI microplate dimensions, allowing seamless integration into automated plate washers and luminescence readers.

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