Corning Microplate with Lid 96 Well TC-Treated Polystyrene Case of 100 Plates

Corning® 96-Well Clear Flat-Bottom Tissue Culture-Treated Microplates with Lids (3917) – Case of 100

The Corning® 3917 is an industry-standard, optical-grade cell culture microplate engineered for high-throughput screening, kinetic cellular assays, and general mammalian cell expansion. Fabricated from premium, ultra-clear virgin polystyrene, the growth surface of each well undergoes a proprietary vacuum-gas plasma tissue culture (TC) treatment to insert oxygen-containing functional groups, creating a hydrophilic surface that ensures uniform cell attachment and spreading. Supplied as a commercial facility case of 100 plates with matching lids (individually wrapped in sterile blister packs of 1), this flat-bottom plate configuration maximizes illumination consistency for inverted microscopic monitoring and automated plate reader analysis.

Technical Performance & Design

• Vacuum-Gas Plasma TC-Treatment: The interior well floors are permanently modified with a uniform hydrophilic charge. This surface modification promotes rapid, reproducible cell adhesion, spreading, and division across all 96 wells, minimizing well-to-well variability during quantitative assays.
• Condensation-Control Lid Matrix: Each plate comes paired with a matching polystyrene lid that integrates specialized condensation-reducing rings. These rings align precisely over each individual well to optimize gas exchange while suppressing evaporation and cross-contamination from condensation drift.
• Optical Flat-Bottom Geometry: Precision-molded to eliminate light distortion, focus scattering, and birefringence. The ultra-flat base geometry ensures sharp, uniform focal planes, making these plates ideal for high-resolution inverted micro-imaging and luminescence/absorbance assays.
• Raised Well Rims & Raised Corners: Designed with raised circular well borders to reduce accidental aerosol spillover. The microplate frame also incorporates distinct raised alphanumeric coordinate grids (A1 through H12) for error-free sample tracking and liquid handling automation mapping.

Product Specifications

• Catalog Number / MPN: 3917
• Primary Manufacturer: Corning Life Sciences
• Plate Format Configuration: 96-Well Microplate Grid
• Well Bottom Geometry: Flat Bottom (Optimized for cell attachment and automated plate scanning)
• Surface Chemistry: Tissue Culture (TC) Treated (Hydrophilic surface for adherent cell lines)
• Material Composition: Crystal-grade, USP Class VI virgin polystyrene (Latex-free)
• Total Well Volume Capacity: Nominal 360 µL per well (Recommended working volume: 75 to 200 µL)
• Total Growth Area: Nominal 0.32 cm² per well
• Sterility & Purity: Gamma irradiated (Sterile); Certified Nonpyrogenic to less than 0.1 EU/mL
• Packaging Configuration: Case of 100 Plates with Lids (Individually wrapped in sterile, peel-open blister pouches to protect aseptic boundaries prior to biosafety hood transfer)

Key Benefits & Applications

• High-Throughput Kinetic Screening: Perfectly suited for running proliferation assays, toxicity screens, and transfection optimizations that require continuous readout stability on automated microplate colorimeters.
• Adherent Cell Culture Scale-Up: Provides an ideal, contamination-shielded environment for maintaining primary cell cultures, established cell lines, or expanding clones following single-cell sorting lines.
• Edge-Effect Evaporation Mitigation: The structural layout, paired with the tight-fitting condensation lid, maintains a uniform micro-climate across inner and outer rows, preventing the skewed assay readouts often caused by drying perimeter wells.
• **Liquid Handling Automation Compatibility:** Engineered to meet standard ANSI/SLAS footprint dimensions, ensuring flawless physical integration with automated liquid handling workstations, multi-channel pipettes, and robotic plate stackers.

Corning® is a registered commercial trademark of Corning, Inc. Catalog number 3917 specifies the clear, flat-bottom, TC-treated 96-well configuration supplied with a lid. For specialized luminescence or fluorescence assays where signal cross-talk must be completely eliminated, alternative black-walled or white-walled solid polymer microplates should be selected.