Cytiva Capsule Filter ULTA Prime CG 0.2 um

Cytiva 12410059 ULTA™ Prime CG 0.2 µm Sterilizing-Grade Capsule (with Integrated Tubing)

The Cytiva 12410059 is a premium, single-use sterile filtration assembly designed for the absolute retention of microorganisms in critical biopharmaceutical applications. Featuring the ULTA™ Prime CG (Culture Grade) Polyethersulfone (PES) membrane, this 0.2 µm capsule offers exceptionally high flow rates and high throughput capacity. This specific catalog number is provided as a ready-to-use manifold, complete with integrated platinum-cured silicone tubing for rapid "plug-and-play" deployment. The inherently hydrophilic PES membrane ensures low protein binding and minimal extractables, making it the industry standard for the final sterilization of cell culture media, buffers, and intermediate biological process streams.

Technical Performance and Design

• Sterilizing-Grade PES Membrane: The 0.2 µm rated polyethersulfone membrane is validated for the absolute retention of Brevundimonas diminuta, ensuring a high Sterility Assurance Level (SAL) for sensitive fluids.

• Integrated Tubing Assembly: Supplied with pre-attached, pharmaceutical-grade silicone tubing, which eliminates the need for manual tubing attachment and reduces the risk of aseptic connection failure.

• Optimized Flow Dynamics: The ULTA™ Prime CG geometry is engineered to maximize effective filtration area while maintaining a compact footprint, resulting in high flux even with complex, nutrient-rich media.

• Low Non-Specific Binding: The PES membrane chemistry is naturally low-binding, ensuring that high-value proteins, growth factors, and active ingredients pass through the filter without significant loss of concentration.

Product Specifications

• Catalog Number: 12410059 (Old GE Code: 12-4100-59)

• Media Type: ULTA™ Prime CG (Polyethersulfone / PES)

• Retention Rating: 0.2 µm (Sterilizing Grade)

• Filter Size: 2-inch (approx. 50 mm) Capsule

• Tubing: Platinum-Cured Silicone (Pre-assembled)

• Sterility: Non-sterile (Fully Autoclavable at 121°C); Also available gamma-compatible.

• Regulatory: Meets USP Class VI for Plastics; Certified non-pyrogenic and non-fiber releasing.

Key Benefits & Applications

• Cell Culture Media Sterilization: The primary application for CG-series filters, providing rapid sterilization of aqueous media containing delicate growth supplements.

• Buffer Preparation: Ideal for the final filtration of high-molarity salt solutions and chromatography buffers to ensure an aseptic downstream environment.

• Aseptic Filling: Suitable for small-batch clinical trial manufacturing where a reliable, low-hold-up-volume sterile filter is required for final product containers.

• Single-Use Integration: As part of the ReadyCircuit™ ecosystem, this capsule seamlessly connects to single-use bags and bioreactors, accelerating process setup times in multi-product facilities.

All product names, logos, and brands are property of their respective owners. ULTA and ReadyMate are trademarks of Cytiva (Global Life Sciences Solutions USA LLC).