Cytiva Capsule Filter ULTA Prime GF 0.6 um

Cytiva 12410068 ULTA™ Prime GF 0.6 µm Capsule Filter Assembly (with Integrated Tubing)

The Cytiva 12410068 is a high-capacity, single-use depth filtration assembly designed for the clarification and pre-filtration of biological fluids. Featuring the ULTA™ Prime GF (Glass Fiber) media with a 0.6 µm retention rating, this capsule is engineered to remove high loads of particulates, lipids, and colloidal matter that would otherwise foul downstream sterilizing-grade filters. This specific catalog number is provided as a complete, ready-to-use manifold, including pre-assembled platinum-cured silicone tubing. This integrated design minimizes assembly time and reduces the risk of bypass or contamination, making it an essential component for upstream harvest and primary clarification in vaccine and monoclonal antibody production.

Technical Performance and Design

• High-Efficiency Glass Fiber Media: The 0.6 µm GF depth matrix provides an exceptionally high dirt-holding capacity, utilizing both surface and depth filtration mechanisms to extend the life of secondary filters.

• Integrated Tubing Manifold: Supplied with pre-attached, high-purity silicone tubing, allowing for immediate "plug-and-play" integration with peristaltic pumps and single-use bioreactors.

• Broad Chemical Compatibility: The all-polypropylene housing and borosilicate glass fiber media offer excellent resistance across a wide pH range (1–14), compatible with most buffer systems and cleaning agents.

• Low Extractable Profile: Manufactured from pharmaceutical-grade materials that meet USP Class VI requirements, ensuring the purity and stability of the processed biological product.

Product Specifications

• Catalog Number: 12410068 (Old GE Code: 12-4100-68)

• Media Type: ULTA™ Prime GF (Borosilicate Glass Fiber)

• Retention Rating: 0.6 µm

• Filter Diameter: 2-inch (approx. 50 mm) Capsule

• Tubing: Platinum-Cured Silicone (Pre-attached)

• Sterility: Non-sterile (Autoclavable at 121°C / 131°C)

• Biological Safety: Meets USP Class VI for Plastics; Non-pyrogenic.

Key Benefits & Applications

• Primary Clarification: Ideally suited for the initial "roughing" filtration of cell culture supernatants and fermentation broths to remove whole cells and large debris.

• Serum & Media Filtration: Effectively removes lipids and protein aggregates from serum-supplemented media, preventing "blinding" of final 0.2 µm sterilizing filters.

• Process Scale-Down: The 2-inch capsule size is perfect for pilot-scale process development and filterability studies before transitioning to full-scale ULTA production cartridges.

• Disposable Convenience: As a single-use assembly, it eliminates the need for housing cleaning and cleaning validation, accelerating batch turnaround times in multi-product facilities.

All product names, logos, and brands are property of their respective owners. ULTA and ReadyCircuit are trademarks of Cytiva (Global Life Sciences Solutions USA LLC).