Cytiva Filter Heater Compatible with Xuri Cell Expansion System W25

Cytiva 29-0444-71 Filter Heater for Xuri™ Cell Expansion System W25

The Cytiva 29-0444-71 is a dedicated thermal management accessory engineered for use with the Xuri™ Cell Expansion System W25 and ReadyToProcess WAVE™ 25 rocking bioreactors. This filter heater is designed to be placed around the exhaust (outlet) air filter of a single-use Cellbag™ bioreactor. By maintaining the filter at an elevated temperature, it effectively prevents the condensation of water vapor from the humidified headspace of the culture. This is a mission-critical safety component in cell therapy manufacturing, as it ensures the exhaust path remains unobstructed, preventing pressure buildup and maintaining the precise gas exchange parameters required for high-density T-cell expansion.

Technical Performance and Design

• Condensation Prevention: Specifically designed to keep the hydrophobic vent filter dry, ensuring that CO2 and O2 exchange remain consistent throughout the duration of the cell expansion process.

• Plug-and-Play Integration: Features a specialized connector that interfaces directly with the Xuri™ W25 CBCU (Cellbag Control Unit) or the WAVE™ 25 Rocker, allowing the UNICORN™ software to monitor and control the heater's status.

• Durable & Cleanable Design: Constructed with a robust, chemically resistant outer shell that can be easily wiped down with standard laboratory disinfectants (such as 70% IPA) to maintain cleanroom compliance.

• Self-Regulating Safety: Engineered to provide consistent localized heating (typically 32VDC / 4W) without risking damage to the single-use filter media or the plastic housing of the Cellbag.

Product Specifications

• Catalog Number: 29-0444-71 (Code No: 29036750)

• Compatibility: Cytiva Xuri™ W25, ReadyToProcess WAVE™ 25

• Power Requirements: 32V DC, 4W

• Application: Exhaust Air Filter Heating

• Material: High-performance polymer / Heat-conductive core

• Connector Type: Specific 4-pin/6-pin circular connector for W25/WAVE 25 series.

Key Benefits & Applications

• Closed-System Integrity: Essential for maintaining the functionally closed environment of the Xuri™ system, especially during long-term perfusion cultures where humidity levels are high.

• T-Cell & Immunotherapy Manufacturing: Standard equipment in CAR-T and TCR process development, where any interruption in gas flow can impact cell viability and phenotype.

• Risk Mitigation: Prevents the "filter blinding" phenomenon, which is the leading cause of pressure-related bag ruptures in rocking bioreactor systems.

• Regulated Environments: Manufactured to the high quality standards required for cGMP manufacturing, ensuring consistent performance across clinical and commercial batches.

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