Cytiva GE Hollow Fiber Filter Tangential Flow Cartridge 0.1 um

Cytiva CFP-1-E-3MA Hollow Fiber TFF Cartridge (0.1 µm, 110 cm²)

The Cytiva CFP-1-E-3MA is a precision-engineered Tangential Flow Filtration (TFF) hollow fiber cartridge designed for microfiltration applications in laboratory and R&D environments. Featuring a 0.1 µm pore size and a 110 cm² effective filtration area, this cartridge is optimized for the clarification and concentration of biological suspensions. The membrane is constructed from Low Adsorption Polyethersulfone (PES) to ensure high permeate flux and maximum product recovery, while the housing is made of rugged Polysulfone (PS). Equipped with 1/2-inch Sanitary Flange (TC) process connections and secondary hose barb ports, this module is a versatile solution for QuixStand and Midgee-scale TFF systems.

Technical Performance and Design

• Microza Low Adsorption PES: The high-flux Polyethersulfone membrane is engineered to minimize non-specific protein binding and fouling, ensuring stable performance during the clarification of cell cultures and lysates.

• 1.0 mm Fiber Lumen: The 1.0 mm internal diameter provides a gentle, low-shear flow path, making it ideal for handling shear-sensitive cells and moderately viscous fluids without clogging.

• Hybrid Connectivity: Features 1/2-inch TC (Tri-Clamp) inlet/outlet ports for a secure, pharmaceutical-grade seal, complemented by integrated hose barbs for easy permeate line attachment.

• Compact Size 3 Housing: With an 110 cm² surface area, this cartridge is the "workhorse" for small-batch processing, allowing for efficient concentration and diafiltration of volumes ranging from 100 ml to 2 Liters.

Product Specifications

• Catalog Number: CFP-1-E-3MA (56-4101-72)

• Pore Size: 0.1 µm (Microfiltration)

• Membrane Area: 110 cm²

• Lumen ID: 1.0 mm

• Materials: PES Membrane; Polysulfone (PS) Housing

• Connections: 1/2-inch TC (Process) and Hose Barb (Permeate)

• Sterility/Sanitation: Autoclavable; compatible with standard NaOH cleaning protocols.

Key Benefits & Applications

• Cell Harvest & Clarification: Optimized for the removal of bacteria, yeast, or mammalian cells from fermentation broth with high yield and low transmembrane pressure.

• Viral Vector Concentration: Provides a low-shear environment essential for the purification of large viruses (e.g., AAV, Lentivirus) where maintaining biological activity is paramount.

• Scalability: The performance data generated with the 3MA cartridge is directly scalable to larger 4MA or production-sized cartridges, reducing process development time.

• Ready for Automation: Fully compatible with automated TFF systems, providing the physical durability required for multiple reuse cycles when properly cleaned.

All product names, logos, and brands are property of their respective owners. Microza is a trademark of Asahi Kasei Medical Co., Ltd.