{"product_id":"cytiva-ge-hollow-fiber-filter-tangential-flow-cartridge-0-1um","title":"Cytiva GE Hollow Fiber Filter Tangential Flow Cartridge 0.1um","description":"\u003ch3\u003eCytiva 56-4101-80 Hollow Fiber TFF Cartridge (0.1 µm, CFP-1-E-4MA)\u003c\/h3\u003e\n\u003cp\u003eThe Cytiva 56-4101-80 (Model CFP-1-E-4MA) is a high-performance Tangential Flow Filtration (TFF) hollow fiber cartridge engineered for the clarification and concentration of biological suspensions. Featuring a 0.1 µm microfiltration membrane, this cartridge is constructed with Low Adsorption Polyethersulfone (PES), designed to provide high permeate flux while minimizing non-specific binding of proteins and other biomolecules. The \"Size 4\" housing and 1.0 mm fiber lumen diameter make it ideal for pilot-scale processing and small-batch production, providing the robust physical integrity required for repeated CIP (Clean-in-Place) and sterilization cycles.\u003c\/p\u003e\n\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMicroza Low Adsorption PES:\u003c\/b\u003e The proprietary membrane chemistry offers a high degree of hydrophilicity, significantly reducing membrane fouling and ensuring stable flux rates during extended clarification runs.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e1.0 mm Fiber Lumen:\u003c\/b\u003e The larger 1.0 mm internal diameter is optimized for handling moderately viscous fluids and high-density cell suspensions, reducing the risk of fiber clogging compared to narrower lumen alternatives.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHigh Surface Area Efficiency:\u003c\/b\u003e The \"4MA\" configuration provides a balanced membrane area (approx. 420 cm²) suitable for QuixStand and Midgee-scale systems, allowing for seamless linear scale-up to larger production modules.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRugged Polysulfone Housing:\u003c\/b\u003e The cartridge is encased in a durable polysulfone shell with standard 1\/2-inch sanitary fittings, ensuring a secure, leak-proof connection to process piping and automation platforms.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 56-4101-80 (CFP-1-E-4MA)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePore Size:\u003c\/b\u003e 0.1 µm (Microfiltration)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Material:\u003c\/b\u003e Low Adsorption Polyethersulfone (PES)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLumen ID:\u003c\/b\u003e 1.0 mm\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCartridge Size:\u003c\/b\u003e Size 4 (Approx. 30 cm length)\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eConnections:\u003c\/b\u003e 1\/2-inch Sanitary Flange (TC) Inlet\/Outlet and Permeate\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterilization:\u003c\/b\u003e Autoclavable and compatible with Sodium Hydroxide (NaOH) sanitation.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCell Harvesting \u0026amp; Clarification:\u003c\/b\u003e The 0.1 µm pore size is specifically designed for the removal of whole cells and large cellular debris from mammalian, bacterial, or yeast fermentation broths.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eViral Vector Concentration:\u003c\/b\u003e Effectively used in the purification of large viral particles (such as Lentivirus or Adenovirus) where high recovery and low shear stress are paramount.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterile Filtration Pre-step:\u003c\/b\u003e Acts as an ideal pre-filter to 0.22 µm sterile membranes, removing bulk contaminants and extending the life of downstream pleated cartridges.\u003c\/p\u003e\u003c\/li\u003e\n  \u003cli\u003e\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow Shear Processing:\u003c\/b\u003e The hollow fiber geometry provides a gentle flow path with uniform shear, protecting shear-sensitive proteins and cells from degradation during the concentration process.\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners. Microza is a trademark of Asahi Kasei Medical Co., Ltd.\u003c\/i\u003e\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"Default Title","offer_id":44497088839932,"sku":"3985","price":225.15,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/cytiva-ge-hollow-fiber-filter-tangential-flow-cartridge-01-um-filters-ge-325474.jpg?v=1778281316","url":"https:\/\/lifesciencestrading.com\/products\/cytiva-ge-hollow-fiber-filter-tangential-flow-cartridge-0-1um","provider":"Life Sciences Trading","version":"1.0","type":"link"}