{"product_id":"cytiva-hollow-fiber-filter-cartridge-0-1-um-850-cm2","title":"Cytiva Hollow Fiber Filter Cartridge 0.1 um 850 cm2","description":"\u003ch3\u003eCytiva RTPCFP-1-E-4X2MS Hollow Fiber Filter – 0.1 µm, 850 cm², Ready-to-Process\u003c\/h3\u003e\n\u003cp\u003eThe Cytiva RTPCFP-1-E-4X2MS is a premium, single-use hollow fiber cartridge engineered for high-efficiency cross-flow filtration in biopharmaceutical development. Featuring a 0.1 µm pore size microfiltration membrane, this cartridge is optimized for the clarification of cell lysates, harvesting of mammalian or bacterial cells, and sterile filtration of complex biological fluids. As part of the Ready-to-Process (RTP) series, the unit is supplied pre-sterilized via gamma irradiation, eliminating the need for time-consuming cleaning validation and autoclaving. The 850 cm² effective filtration area and robust polyethersulfone (PES) membrane chemistry provide high flux rates and exceptionally low protein binding, ensuring maximum recovery of high-value proteins and viral vectors.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eGamma-Sterilized (RTP):\u003c\/b\u003e Delivered pre-sterilized and ready for immediate integration into aseptic closed-loop systems, significantly reducing setup time and the risk of batch contamination.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003e0.1 µm Polyethersulfone (PES) Membrane:\u003c\/b\u003e Features a highly asymmetric pore structure that provides superior retention of fine particulates and microorganisms while maintaining high flow velocities.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eLow Non-Specific Binding:\u003c\/b\u003e The modified PES membrane is designed to minimize the adsorption of proteins and nucleic acids, ensuring the integrity and yield of the final product.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHollow Fiber Geometry:\u003c\/b\u003e The open-channel design is exceptionally tolerant of high-solids loading and turbid feedstreams, making it less prone to fouling than traditional flat-sheet TFF cassettes.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e RTPCFP-1-E-4X2MS\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003ePore Size:\u003c\/b\u003e 0.1 µm\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSurface Area:\u003c\/b\u003e 850 cm² (0.085 m²)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eFiber ID:\u003c\/b\u003e 1.0 mm (optimized for medium-viscosity feeds)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMembrane Material:\u003c\/b\u003e Low-protein binding Polyethersulfone (PES)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eHousing Material:\u003c\/b\u003e Polysulfone\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility:\u003c\/b\u003e Sterile (Gamma Irradiated)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCell Harvest \u0026amp; Clarification:\u003c\/b\u003e The ideal choice for the primary recovery of cells and the removal of cell debris from fermentation broths in both upstream and downstream processing.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eViral Vector Purification:\u003c\/b\u003e Extensively used in the production of AAV and Lentivirus, where gentle processing and high surface area are required to maintain viral titer and purity.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eScalable Performance:\u003c\/b\u003e The 850 cm² format provides a perfect scale-down model for larger production-scale hollow fiber systems, allowing for predictable process development.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eDisposable Efficiency:\u003c\/b\u003e As a single-use cartridge, it supports the rapid turnaround of multi-product facilities by eliminating the resource-intensive requirements of CIP (Clean-in-Place) and SIP (Steam-in-Place).\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eExpiration Date: 2020-10\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e","brand":"Cytiva","offers":[{"title":"Default Title","offer_id":44498091344124,"sku":"4196","price":416.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/cytiva-hollow-fiber-filter-cartridge-01-um-850-cm2-filters-cytiva-169044.jpg?v=1765333380","url":"https:\/\/lifesciencestrading.com\/products\/cytiva-hollow-fiber-filter-cartridge-0-1-um-850-cm2","provider":"Life Sciences Trading","version":"1.0","type":"link"}