{"product_id":"eppendorf-bioblu-bioreactor-3c-sterile-5-l-single-use","title":"Eppendorf BioBLU Bioreactor 3c Sterile 5 L Single Use","description":"\u003ch3\u003eEppendorf BioBLU 3c Single-Use Bioreactor – 5 L, Macrosparger, Pitched-Blade Impeller, Sterile\u003c\/h3\u003e\n\u003cp\u003eThe Eppendorf 1386000300 BioBLU 3c is a premier single-use bioreactor designed to provide the performance of a traditional stirred-tank vessel with the convenience and safety of disposable technology. This 5-liter rigid-wall vessel is specifically optimized for mammalian cell culture, featuring a single pitched-blade impeller that provides gentle, low-shear mixing essential for sensitive cell lines such as CHO, HEK293, and stem cells. The macrosparger configuration is ideal for high-density cultures where efficient gassing is required with minimal foaming. Supplied fully sterile and pre-assembled with non-invasive optical sensors, the BioBLU 3c eliminates the need for cleaning, autoclaving, and probe insertion, significantly reducing the risk of contamination and increasing laboratory throughput.\u003c\/p\u003e\n\u003ch3\u003eTechnical Performance and Design\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRigid-Wall Stirred-Tank Design:\u003c\/b\u003e Combines the proven geometry of glass bioreactors with the benefits of single-use materials, ensuring easy scale-up and consistent mixing dynamics across the BioBLU portfolio.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMacrosparger Gassing:\u003c\/b\u003e Features a macrosparger for submerged aeration, providing excellent mass transfer while reducing the small-bubble shear stress and foaming often associated with microspargers.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eNon-Invasive Optical Sensors:\u003c\/b\u003e Pre-installed optical \"spots\" for pH and Dissolved Oxygen (DO) allow for real-time monitoring through the vessel wall, eliminating the contamination risks associated with traditional probe insertion.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMagnetic Overhead Drive:\u003c\/b\u003e Utilizing a sealed magnetic coupling for the impeller, this design ensures a complete microbial barrier and maintains vessel integrity throughout long-term cultures.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eProduct Specifications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCatalog Number:\u003c\/b\u003e 1386000300\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eTotal Volume:\u003c\/b\u003e 5.0 L\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eWorking Volume Range:\u003c\/b\u003e 1.25 L – 3.75 L\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eImpeller Type:\u003c\/b\u003e 1 x Pitched-Blade Impeller (Down-flow)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSparger Type:\u003c\/b\u003e Macrosparger\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eMaterial:\u003c\/b\u003e USP Class VI Polycarbonate (Animal Component-Free)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eSterility:\u003c\/b\u003e Sterile (Irradiated, SAL 10⁻⁶)\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch3\u003eKey Benefits \u0026amp; Applications\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eBioprocess Scale-Up:\u003c\/b\u003e Geometrically similar to the BioBLU 0.3c and 50c models, making it a critical tool for bridging the gap between small-scale R\u0026amp;D and pilot-scale production.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eRisk Mitigation:\u003c\/b\u003e The single-use nature eliminates cross-contamination between runs and the need for complex cleaning validation (CIP\/SIP) procedures.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eCell and Gene Therapy:\u003c\/b\u003e Optimized for high-value suspension cultures where sterile integrity and low-shear environments are non-negotiable for maintaining cell viability and titer.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cp style=\"margin: 0;\"\u003e\u003cb\u003eController Compatibility:\u003c\/b\u003e Seamlessly integrates with Eppendorf BioFlo 120 and BioFlo 320 control stations, as well as various legacy and third-party systems via available adapter kits.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eExpiration: 2024-02.\u003c\/strong\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003cp style=\"margin: 0; font-size: 0.8em;\"\u003e\u003ci\u003eAll product names, logos, and brands are property of their respective owners.\u003c\/i\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"Eppendorf","offers":[{"title":"Default Title","offer_id":44498054119676,"sku":"4176","price":812.25,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0627\/8463\/5132\/files\/eppendorf-bioblu-bioreactor-3c-sterile-5-l-single-use-bioreactors-fermenters-eppendorf-405705.jpg?v=1767914865","url":"https:\/\/lifesciencestrading.com\/products\/eppendorf-bioblu-bioreactor-3c-sterile-5-l-single-use","provider":"Life Sciences Trading","version":"1.0","type":"link"}