Eppendorf DNA LoBind Centrifuge Tube 0.5 ml - Total of 100 Tubes

Eppendorf DNA LoBind Safe-Lock Microcentrifuge Tubes – 0.5 mL, Clear Virgin Polypropylene, Conical Bottom, PCR Clean Purity Grade, High Recovery, Rated to 30,000 x g (MPN: 022431005)

The Eppendorf 022431005 (also cataloged as 22431005 or cross-listed under Fisher Scientific as 13-698-790) is a premium, molecular-biology-grade microcentrifuge tube engineered to ensure maximum sample recovery of nucleic acids during preparation, quantification, and long-term storage. Precision-molded from high-purity virgin polypropylene, these 0.5 mL (500 microliter) tubes utilize a specialized manufacturing technology that alters the internal polymer matrix to drastically reduce sample-to-surface binding. Unlike traditional low-binding options, this ultra-low retention effect is achieved completely without the use of surface coatings or chemical additives (such as silicone), eliminating the risk of sample contamination or downstream assay interference. Equipped with the legendary Eppendorf Safe-Lock snap cap design, these tubes provide an exceptional mechanical lid seal that minimizes evaporation while safely withstanding extreme centrifugal fields up to 30,000 x g.

Technical Performance and Design

• Proprietary DNA LoBind Solid Matrix: Formed via a specialized polymer blending technique that maximizes nucleic acid recovery (nearly 100%) independent of incubation temperature and time. Because the plastic itself is low-binding, there are no external coatings to leach or degrade over time.

• Hinged Safe-Lock Latching Cap: Outfitted with the industry-standard Safe-Lock snap cap system. The integrated structural hook latch clips securely over the barrel rim, preventing accidental pop-open evaporation during intense thermal cycler steps, boiling water baths, or deep-freeze cycles.

• Extreme 30,000 x g Centrifugal Rating: Features heavy-duty, structurally reinforced conical base walls validated to withstand continuous relative centrifugal forces up to 30,000 x g, making them highly reliable for pelleting, high-speed phase extractions, and complex genomic separation passes.

• Lot-Certified PCR Clean Purity: Manufactured under fully automated, human-contact-free cleanroom parameters. Every batch is independently lot-tested and certified free of detectable human DNA, DNase, RNase, and molecular PCR inhibitors to safeguard ultra-trace forensic or clinical genetic samples.

Product Specifications

• Catalog Number / MPN: 022431005 (Cross-listed as 22431005 / 13-698-790 / 1231A75)

• Manufacturer / Brand: Eppendorf AG

• Volumetric Capacity: 0.5 mL (500 microliters)

• Color Silhouette: Colorless / Optically Clear

• Bottom Shape Style: Conical Base

• Closure Type Profile: Attached Hinged Safe-Lock Snap Cap (Includes a frosted matte exterior labeling surface)

• Material Composition: Pure Translucent Natural Virgin Polypropylene (PP)

• Sterility Metric: Non-Sterile (Lot-Certified PCR Clean Purity Grade; fully autoclavable at 121 C for 20 minutes)

• Standard Case Configuration: Box / Pack of 250 Tubes total (Divided into 5 convenient inner bags containing 50 tubes each)

Key Benefits and Applications

• Next-Generation Sequencing (NGS) Prep: The absolute gold standard container choice for preparing low-concentration genomic libraries, managing absolute qPCR dilution series, and handling rare trace DNA samples where tube-wall sticking degrades sequencing metrics.

• Forensic Trace Analysis: High-purity clean claims and lot certifications ensure that low-copy-number DNA collected from crime scenes remains fully unbound and clear of background biological noise for clean amplification loops.

• High-Precision Quantitative Assays: Low-binding properties prevent analyte concentration drift over prolonged storage windows, ensuring outstanding calibration accuracy during real-time absolute quantifications.

• Molded Volumetric Graduation Scale: Crisp, embossed external graduation markings run up the side profile to facilitate immediate volume checking, paired with a flat cap face optimized for smear-free marker labeling.

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