Greiner Bio-One Microplate 96 Well Polystyrene V-Bottom Case of 40 Plates

Greiner Bio-One® 96-Well Clear Microplate, Polystyrene, Conical V-Bottom, Non-Binding (651901) – Case of 40

The Greiner Bio-One® 651901 is a high-performance, automation-friendly 96-well microplate specifically engineered for sensitive biochemical assays, sample storage, and clinical screening applications. Featuring a specialized conical V-bottom well profile, this plate is optimized for precise sample recovery, allowing liquid handling systems to pipette off the entire volume as liquid pools efficiently at the narrow apex. Fabricated from premium, optically clear polystyrene treated with a proprietary non-binding surface modification, it reduces non-specific binding of proteins, DNA, RNA, and peptides to maximize the signal-to-noise ratio. Supplied as a commercial case of 40 plates (packaged as 4 convenient sleeves of 10), this multi-well consumable is manufactured under strict cleanroom guidelines to ensure absolute assay purity.

Technical Performance & Design

• Proprietary Non-Binding Surface Technology: Treated with a specialized modification that stable-coats the polystyrene matrix. This barrier prevents non-specific adsorption of biomolecules (like low-concentration peptides or nucleic acids), reducing unwanted background noise and maximizing signal intensity.
• Conical V-Bottom Geometry: The sharp conical base profile gathers fluid volume at the dead center of the well bottom. This minimizes dead volume during automated aspiration loops and makes it ideal for protocols requiring precise sample recovery or sediment collection.
• Isotropic Optical Clarity: Injection-molded from specialized, high-clarity clear virgin polystyrene (PS). This allows accurate top-read and bottom-read colorimetric, spectrophotometric, and optical density evaluations across microplate readers.
• Standardized SLAS/ANSI Footprint: Precision machined to meet Society for Laboratory Automation and Screening dimensional requirements. The rigid design prevents warping under high thermal gradients or structural loads, ensuring seamless integration with microplate stackers, shakers, and automated handlers.

Product Specifications

• Model Number / SKU: 651901 (Non-Binding Assay Series)
• Primary Manufacturer: Greiner Bio-One® International GmbH
• Well Configuration Matrix: Standard 96-well grid format ($12 \times 8$ layout)
• Well Bottom Geometry: Conical V-Bottom (Solid well construction)
• Surface Modification Class: Non-Binding (Low protein, DNA, RNA, and peptide adsorption)
• Material Chemistry: 100% High-Grade Clear Polystyrene (PS / Non-Sterile)
• Lid Inclusion Status: Supplied without lids (Compatible Greiner plate lids must be sourced independently)
• Purity Certifications: Certified free of detectable RNase, DNase, human DNA, and pyrogens/endotoxins
• Packaging Configuration: Case of 40 Plates (Packaged as 4 sealed bags containing 10 plates each)

Key Benefits & Applications

• Sensitive Biochemical Assays: Excellent for homogenous assays, fluorescence, and luminescence assays where low amounts of biomolecular wall-binding typically skew quantitative concentration parameters.
• High-Recovery Sample Storage: Highly recommended for storing small-volume chemical libraries or rare biological derivatives, ensuring the sample can be extracted with minimal liquid residue left behind.
• Automated Liquid Handling Compatibility: Uniform physical dimensions and precise well centering coordinates eliminate alignment drift when working with multi-channel electronic pipettors or robotic liquid handlers.
• Comprehensive Lot Traceability: Manufactured under strict DIN ISO 9001 quality guidelines, every package features a defined production LOT number system to allow complete history validation.

Greiner Bio-One® and μClear® are registered commercial trademarks of Greiner Bio-One International GmbH. Part number 651901 specifies the non-binding, clear polystyrene 96-well V-bottom model. For protocols involving harsh organic solvents like DMSO or requiring high-temperature incubation loops, alternative polypropylene (PP) storage configurations must be substituted.