Integra 6545 Pipette Tip 1250 ul GripTip Sterile Low Retention 5 Racks with 96 Tips Each

Integra Biosciences® GripTip™ 1250 µL Low-Retention Sterile Filtered Pipette Tips, XYZ Racks (6545) – Case of 480 Tips

The Integra Biosciences® 6545 is a premium, high-volume liquid handling consumable engineered for critical molecular biology, clinical diagnostics, and automated liquid handling workflows. Utilizing Integra’s proprietary GripTip™ snap-on locking design, these large-volume 1250 µL tips eliminate typical friction-fit seating errors, ensuring they lock tightly onto the pipette shaft and never loosen, leak, or drop off mid-protocol. Outfitted with an ultra-smooth **Low-Retention surface modification** and an integrated high-density aerosol barrier, these tips are supplied pre-sterilized and arranged in 96-well configurations across a case of 5 reinforced XYZ racks of 96 tips each (480 total tips) to maintain absolute aseptic sample isolation.

Technical Performance & Design

• Proprietary GripTip™ Interlocking Collar: Features a precision-molded internal shoulder that snaps tightly over matching multi-channel shaft lobes. This mechanical connection ensures all tips sit at exactly the same vertical height across a multi-channel head, providing perfect alignment and leak-proof seals without forceful jamming.
• Ultra-Hydrophobic Low-Retention Polymer: The internal polypropylene structure utilizes specialized resin technology to lower surface energy. This prevents viscous or low-surface-tension fluids (like master mixes, glycerol, and detergent-rich buffers) from binding or wetting the inner tip walls, guaranteeing high sample recovery.
• High-Efficiency Aerosol Protection Filter: Outfitted with an integrated hydrophobic polyethylene (PE) filter barrier. This matrix blocks airborne vapors, liquids, and aerosols from traveling up into the internal pipette barrel, protecting your equipment from corrosive sample carryover and preventing sample-to-sample cross-contamination.
• Heavy-Duty Carbon-Reinforced XYZ Racks: Racked within specialized, extra-rigid XYZ structural bases. These heavy-duty racks are designed to absorb the high downward forces required during multi-channel manual or automated loading without flexing, guaranteeing crisp alignment.

Product Specifications

• Model Number / SKU: 6545 (GripTip™ High Volume Series)
• Primary Manufacturer: Integra Biosciences® Corp.
• Maximum Volumetric Capacity: 1250 µL (Designed for large-volume aliquoting and master mix preparation)
• Tip Fitment Interface: Integra GripTip™ System (Compatible with 1000 µL and 1250 µL manual/electronic single or multi-channel Integra pipettes, VIAFLO 96/384 heads, and the ASSIST PLUS platform)
• Fluid Retention Class: Low-Retention (Hydrophobic inner matrix)
• Sterility Status: Gamma Radiation Sterilized Baseline
• Purity Verification: Certified free of detectable RNase, DNase, Endotoxins, Pyrogens, and PCR Inhibitors
• Packaging Configuration: Case of 480 Tips (5 rigid XYZ racks holding 96 tips each in a standard 8x12 grid)

Key Benefits & Applications

• High-Volume Master Mix Preparation: Excellent for dispensing bulk enzyme solutions, lysis buffers, and foaming reagents where fluid retention within the barrel tip would skew quantitative downstream values.
• Automated High-Throughput Liquid Handling: The structural rigidity of the XYZ rack coordinates precisely with the mechanical axes of automated workstations like the Integra ASSIST PLUS, preventing pick-up errors.
• Deep-Vessel Reagent Aliquoting: Extended high-volume tip configuration provides a clean fluid release and deep vessel reach, minimizing the risk of the pipette shaft scraping against the walls of 15 mL conical tubes.
• Aseptic Tissue Culture Work: Pre-sterilized, certified pure validation shields delicate tissue culture media steps, downstream genomic extractions, and cellular assays from ambient laboratory contamination.

Integra®, GripTip™, VIAFLO®, and ASSIST PLUS® are registered trademarks of Integra Biosciences Group. Part number 6545 specifies the sterile filtered, low-retention 1250 µL model pre-arranged in rigid 96-tip XYZ Racks. For less sensitive washing loops or standard aqueous buffer transfers, alternative standard non-filtered components or eco-friendly refill packs may be substituted.