Integra Biosciences Pipette Tip 300 ul Sterile Wide Bore 2 Packs - 10 Racks

Integra Biosciences GripTip 300 µL Wide-Bore Sterile Non-Filtered Pipette Tips, XYZ Racks (6634) 2 Cases - 960 Tips

The Integra Biosciences 6634 is a specialized liquid handling consumable engineered for processing delicate biological samples, high-viscosity liquids, and cellular suspensions. Utilizing Integra's proprietary GripTip snap-on connection mechanics, these 300 µL tips eliminate typical friction-fit errors by locking firmly onto the pipette shaft to prevent shifting, loosening, or accidental drop-offs. Designed with an expanded Wide-Bore orifice tip geometry, this consumable dramatically reduces fluid shear forces, ensuring high sample viability during delicate cellular manipulation loops. The tips are supplied pre-sterilized and arranged in standard 96-well configurations across a case of 5 reinforced XYZ racks of 96 tips each (960 total tips).

Technical Performance & Design

• Enlarged Wide-Bore Orifice Exit: Engineered with a significantly wider internal diameter at the dispensing tip orifice compared to standard 300 µL tips. This geometry reduces the velocity and pressure drop of liquids during aspiration, dramatically lowering mechanical shear stress on fragile cell lines and genomic macromolecules.
• Proprietary GripTip™ Interlocking Collar: Features a precision-molded internal shoulder ring that snaps tightly over matching multi-channel shaft lobes. This mechanical connection ensures all tips sit at exactly the same vertical height across a multi-channel head, providing perfect alignment and leak-proof seals without forceful jamming.
• High-Viscosity Fluid Flow Paths: The wider aperture lowers flow resistance, making it easier to aspirate and dispense heavy, viscous liquids like glycerol, pure resins, oils, and concentrated protein mixtures without lagging or air gap contamination.
• Heavy-Duty Carbon-Reinforced XYZ Racks: Racked within specialized, extra-rigid XYZ structural bases. These heavy-duty racks are designed to absorb the high downward forces required during multi-channel manual or automated loading without flexing, guaranteeing crisp alignment.

Product Specifications

• Model Number / SKU: 6634 (GripTip Specialized Wide-Bore Series)
• Primary Manufacturer: Integra Biosciences Corp.
• Maximum Volumetric Capacity: 300 µL (Optimized for cell culture seeding and genomic transfers)
• Tip Fitment Interface: Integra GripTip System (Compatible with 50 µL, 100 µL, and 300 µL manual/electronic single or multi-channel Integra pipettes, VIAFLO 96/384 heads, and the ASSIST PLUS platform)
• Orifice Tip Profile: Wide-Bore (Aperture optimized for minimal fluid shear friction)
• Sterility Status: Gamma Radiation Sterilized Baseline
• Purity Verification: Certified free of detectable RNase, DNase, Endotoxins, Pyrogens, and PCR Inhibitors
• Packaging Configuration: Case of 480 Tips (5 rigid XYZ racks holding 96 tips each in a standard 8x12 grid)

Key Benefits & Applications

• Intact Fragile Cell Line Transfers: Highly recommended for aspirating and dispensing delicate cell suspensions (such as stem cells, primary cells, or fragile mammalian cultures) where standard narrow apertures can rupture cell membranes and reduce sample viability.
• High-Molecular-Weight DNA Handling: Prevents fragmentation and shearing when manipulating genomic DNA (gDNA) or long-read sequencing libraries, maintaining the structural sequence length of macro-nucleotides.
• Automated Cell Culture Seeding: The structural stability of the heavy-duty XYZ rack coordinates precisely with the mechanical axes of automated workstations like the Integra ASSIST PLUS, preventing alignment faults during automated tip loading.
• Thick Reagent and Glycerol Aliquoting: Streamlines handling of sticky storage agents, enzymatic master mixes, and detergent-heavy reagents by enabling uniform liquid entry and clean fluid release profiles.